Risk Factors for Endometrial Cancer in Black Women

NCT00514254 | Active Not Recruiting

• 3 other identifiers: 07-093P30CA008748MSKCC-07093
• Study Type: observational
• Target: 59
• Locations: 1 country
• Sites: 4

Brief Summary

RATIONALE: Learning about the risk factors for endometrial cancer in black women may help the study of endometrial cancer in the future. PURPOSE: This clinical trial is studying risk factors for endometrial cancer in black women.

Conditions

Endometrial Cancer

Keywords

endometrial cancer; risk factors; questionnaire; 07-093

Outcome Measures

Primary Outcomes (8)

• Number and percentage of potential cases and controls approached who are found to be eligible for the study and reasons for being ineligible (including language)

  2 years

• Number and percentage of cases and controls approached who sign informed consent

  2 years

• Number and percentage of cases and controls who complete each part of the study (main questionnaire, diet questionnaire, saliva/buccal specimen)

  2 years

• Proportion of questions with missing data

  2 years

• Interviewer's evaluation of interview quality and respondent cooperation

  2 years

• Number and percentage of cases who are willing to have tumor specimens used for future research

  2 years

• Characteristics of cases and controls (demographics, main risk factors, and use of health care and screening)

  2 years

• Proportion of participants who rate the study positively on each measure in the post-interview assessment and respondents' suggested changes to the study

  2 years

Study Arms (2)

case

Participants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research.

Other: questionnaire administration; Other: study of socioeconomic and demographic variables; Procedure: evaluation of cancer risk factors

control

Participants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research.

Other: questionnaire administration; Other: study of socioeconomic and demographic variables; Procedure: evaluation of cancer risk factors

Interventions

questionnaire administration OTHER

case; control

study of socioeconomic and demographic variables OTHER

case; control

evaluation of cancer risk factors PROCEDURE

case; control

Eligibility Criteria

• Age: 21 Years+
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Black women (including African-American, African, Afro-Caribbean women) with endometrial cancer and controls will be recruited at MSKCC, SUNY Downstate Medical Center and Montefiore Medical Center hospitals. Controls will be black (including African-American, African, Afro-Caribbean) women without history of cancer, who have intact uteri, and will be identified in gynecology clinics. Controls will also be recruited at the Breast Examination Center of Harlem (BECH), an affiliate of MSKCC, providing high quality screening services to a minority community.

DISEASE CHARACTERISTICS: * Cases * Diagnosed with endometrial cancer within the past year * Self-identified as being black, African-American, black Hispanic, African, or Afro-Caribbean * Healthy controls * Self-identified as being black, African-American, black Hispanic, African, or Afro-Caribbean * No history of endometrial or other cancer (except non-melanoma skin cancer) * No prior hysterectomy PATIENT CHARACTERISTICS: * Speak English * No medical condition that would make it difficult to complete the interview PRIOR CONCURRENT THERAPY: * See Disease Characteristics

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• Memorial Sloan Kettering Cancer Center: lead
• National Cancer Institute (NCI): collaborator
• The City College of New York: collaborator
• DOWNSTATE MED/KINGS CO/BKLYN: collaborator
• Montefiore Medical Center: collaborator

Study Sites (4)

SUNY Downstate Medical Center

Brooklyn, New York, 11203, United States

Location

City College of New York

New York, New York, 10031, United States

Location

Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States

Location

Montefiore Medical Center

The Bronx, New York, 10461, United States

Location

Related Links

• Memorial Sloan Kettering Cancer Center

Biospecimen

Retention: SAMPLES WITH DNA

saliva/buccal specimens

MeSH Terms

Conditions

Endometrial Neoplasms

Condition Hierarchy (Ancestors)

Uterine Neoplasms; Genital Neoplasms, Female; Urogenital Neoplasms; Neoplasms by Site; Neoplasms; Uterine Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases

Study Officials

• Sara Olson, PhD

  Memorial Sloan Kettering Cancer Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 8, 2007
• First Posted: August 9, 2007
• Study Start: July 1, 2007
• Primary Completion (Estimated): July 1, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: August 12, 2025

Record last verified: 2025-08

Locations

US (4)