NCT00513032

Brief Summary

We hypothesized that pre-treatment with methylene blue could potentiate the effects of general anaesthetic agents in patients undergoing parathyroidectomy

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2005

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2005

Completed
2.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2007

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

August 7, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 8, 2007

Completed
Last Updated

August 8, 2007

Status Verified

August 1, 2007

First QC Date

August 7, 2007

Last Update Submit

August 7, 2007

Conditions

Hyperparathyroidism

Keywords

propofolanaesthesia inductionparathyroidectomymethylene blueGeneral anesthesia

Study Arms (2)

methylene blue

Drug: methylene blue

C

Drug: methylene blue

Interventions

methylene blueDRUG

5mg.kg-1 methylene blue in 250 ml 5% glucose-saline, administered intravenously approximately 60 min before anaesthesia induction

Cmethylene blue

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients undergoing parathyroidectomy or partial thyroidectomy

You may not qualify if:

  • Psychiatric disorders
  • Drug abuse
  • Weight 20% more or less than ideal body weight

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Service d'Anesthésiologie, Hôpitaux Universitaires de Genève, Rue Micheli-du-Crest

Geneva, CH-1211, Switzerland

Location

MeSH Terms

Conditions

Hyperparathyroidism

Interventions

Methylene Blue

Condition Hierarchy (Ancestors)

Parathyroid DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

PhenothiazinesSulfur CompoundsOrganic ChemicalsHeterocyclic Compounds, 3-RingHeterocyclic Compounds, Fused-RingHeterocyclic Compounds

Study Officials

  • Marc Licker, MD

    University Hospital, Geneva

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 7, 2007

First Posted

August 8, 2007

Study Start

January 1, 2005

Study Completion

April 1, 2007

Last Updated

August 8, 2007

Record last verified: 2007-08

Locations

CH(1)