NCT00512694

Brief Summary

Lupus is a systemic autoimmune disease that can present with many varied symptoms, including joint pain, fevers, kidney disease, and rashes. Lupus can affect anyone, but it is most common in younger women. The Duke Lupus Registry will collect information and blood samples from patients with lupus (systemic lupus erythematosus or cutaneous lupus) seen in the Duke Rheumatology clinics. The goal of this Registry is to understand how lupus changes over time so that we can improve the treatment of patients with lupus.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
25mo left

Started Jul 2007

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress90%
Jul 2007Jun 2028

Study Start

First participant enrolled

July 1, 2007

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 6, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 8, 2007

Completed
20.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2028

Last Updated

January 8, 2026

Status Verified

January 1, 2026

Enrollment Period

20.9 years

First QC Date

August 6, 2007

Last Update Submit

January 6, 2026

Conditions

Systemic Lupus ErythematosusCutaneous Lupus

Keywords

LupusSystemic Lupus ErythematosusCutaneous Lupus

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Any patients with lupus.

You may qualify if:

  • Diagnosis of Systemic Lupus Erythematosus or Cutaneous Lupus
  • Patient of a rheumatologist at Duke University Medical Center

You may not qualify if:

  • Inability to travel to Duke for follow-up visits
  • Inability to speak English
  • Not able to provide informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Duke University Medical Center

Durham, North Carolina, 27710, United States

RECRUITING

Related Links

Biospecimen

Retention: SAMPLES WITHOUT DNA

Blood samples will be collected for future research.

MeSH Terms

Conditions

Lupus Erythematosus, Systemic

Condition Hierarchy (Ancestors)

Connective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Megan E. B. Clowse, MD, MPH

    Duke University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Laura Neil

CONTACT

(919) 684-8936laura.k.neil@duke.edu

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 6, 2007

First Posted

August 8, 2007

Study Start

July 1, 2007

Primary Completion (Estimated)

June 1, 2028

Study Completion (Estimated)

June 1, 2028

Last Updated

January 8, 2026

Record last verified: 2026-01

Locations

US(1)