NCT00510523

Brief Summary

The purpose of this investigation is to determine the effect of Whole Body Vibration Therapy (WBV) on balance in participants with multiple sclerosis (MS) related balance deficits as measured by the NeuroCom Balance Master, the Sapphire IIME EMG Device and the Kurtzke Expanded Disability Status Scale (EDSS) and the Berg Balance Score.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P75+ for not_applicable multiple-sclerosis

Timeline
Completed

Started Oct 2006

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2006

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

July 31, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 2, 2007

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2007

Completed
Last Updated

May 3, 2013

Status Verified

May 1, 2013

First QC Date

July 31, 2007

Last Update Submit

May 2, 2013

Conditions

Keywords

MSBalanceMultiple Sclerosis

Outcome Measures

Primary Outcomes (3)

  • NeuroCom Balance Master

  • SF-EMG Nerve conduction velocity test

  • Berg balance score

Interventions

Eligibility Criteria

Age25 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Logan student, staff, or faculty or general public with a minimal of 2 year history of diagnosed Multiple Sclerosis (MS)

You may not qualify if:

  • Visual or vestibular condition that would affect balance
  • Non-Ms related systemic illness that would have an adverse effect on balance
  • Local infection, acute inflammation, injury, tumors or other malignancy, recent wounds, diabetes
  • Any unstable joints of the lower extremity, recent hip and knee joints or fitted hip or knee pins, bolts and/or plates
  • Acute thrombosis
  • Severe migraine, epilepsy
  • Serious cardiovascular disease, wearing a pacemaker
  • Any Spinal manipulation within 48 hours
  • Acute disc herniation, discopathy or spondylolysis
  • Prescription or herbal muscle stimulants, relaxants, etc. that could affect balance
  • Any implanted device or prosthesis or intrauterine IUD type of device
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Logan University, College of Chiropractic

Chesterfield, Missouri, 63017, United States

Location

Logan University, College of Chirpractic

Chesterfield, Missouri, 63017, United States

Location

Related Publications (2)

  • Romberg A, Virtanen A, Ruutiainen J, Aunola S, Karppi SL, Vaara M, Surakka J, Pohjolainen T, Seppanen A. Effects of a 6-month exercise program on patients with multiple sclerosis: a randomized study. Neurology. 2004 Dec 14;63(11):2034-8. doi: 10.1212/01.wnl.0000145761.38400.65.

    PMID: 15596746BACKGROUND
  • Griffin JW. Use of proprioceptive stimuli in therapeutic exercise. Phys Ther. 1974 Oct;54(10):1072-9. doi: 10.1093/ptj/54.10.1072. No abstract available.

    PMID: 4422763BACKGROUND

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNSAutoimmune Diseases of the Nervous SystemNervous System DiseasesDemyelinating DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Dennis Enix, DC, MBA

    Logan College of Chiropractic

    PRINCIPAL INVESTIGATOR
  • Dennis Enix, DC, MBA

    Logan University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

July 31, 2007

First Posted

August 2, 2007

Study Start

October 1, 2006

Study Completion

November 1, 2007

Last Updated

May 3, 2013

Record last verified: 2013-05

Locations