NCT00503269

Brief Summary

Background: Local anaesthetic day-care open haemorrhoidectomy (LH) is feasible, cheap and may be the cost-effective surgical approach to third degree haemorrhoids. This prospective randomised controlled trial compares patient's evaluation of LH with general anaesthetic day-care Park's modified Milligan-Morgan haemorrhoidectomy (GH). Methods: 41 patients with third degree haemorrhoids were randomised to LH (19 cases) and GH (22 cases). Demographics were comparable. Independent assessment (by a research nurse) and clinical evaluation ran parallel for 6 months. Outcome measures were average and expected pain scores for 10 days; satisfaction scores at 10 days, 6 weeks and 6 months. Secondary outcomes were journey time and cost in day surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2005

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2005

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2007

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2007

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

July 16, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 18, 2007

Completed
Last Updated

September 14, 2023

Status Verified

September 1, 2023

Enrollment Period

1.9 years

First QC Date

July 16, 2007

Last Update Submit

September 11, 2023

Conditions

Keywords

HaemorrhoidectomyLocal anaesthesia

Outcome Measures

Primary Outcomes (1)

  • Average pain and expectation score.

    6 months

Secondary Outcomes (1)

  • Journey time and cost analysis

    6 months.

Study Arms (2)

1

ACTIVE COMPARATOR

30 ml of 1% Lignocaine with 1:10,000 Adrenaline

Procedure: Hemorrhoidectomy

2

ACTIVE COMPARATOR

Standard General anaesthesia with Enflurane and Propofol.

Procedure: Hemorrhoidectomy

Interventions

Hemorrhoidectomy under local anaesthesia

1

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Third degree haemorrhoids

You may not qualify if:

  • Unfit for day-surgery or general anaesthesia.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Channel day surgery unit

Ashford, Kent, TN24 0LZ, United Kingdom

Location

Related Publications (1)

  • Kushwaha R, Hutchings W, Davies C, Rao NG. Randomized clinical trial comparing day-care open haemorrhoidectomy under local versus general anaesthesia. Br J Surg. 2008 May;95(5):555-63. doi: 10.1002/bjs.6113.

MeSH Terms

Conditions

Hemorrhoids

Interventions

Hemorrhoidectomy

Condition Hierarchy (Ancestors)

Rectal DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System DiseasesVascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Digestive System Surgical ProceduresSurgical Procedures, Operative

Study Officials

  • Nagesh G Rao, FRCS, MD

    East Kent NHS Trust

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 16, 2007

First Posted

July 18, 2007

Study Start

July 1, 2005

Primary Completion

June 1, 2007

Study Completion

July 1, 2007

Last Updated

September 14, 2023

Record last verified: 2023-09

Locations