Multicenter Trial of Daily Chlorhexidine Bathing to Reduce Nosocomial Infections
CBET
Multicenter Evaluation of The Effectiveness of Source Control With Daily Chlorhexidine Skin Preparation in Reducing Nosocomial Infections Including MRSA and VRE
1 other identifier
observational
14,000
1 country
7
Brief Summary
To determine if daily bathing with chlorhexidine impregnated washcloths will reduce the incidence of MRSA and VRE within an Intensive Care Unit (ICU) or ward setting.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Aug 2007
Typical duration for all trials
7 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 16, 2007
CompletedFirst Posted
Study publicly available on registry
July 17, 2007
CompletedStudy Start
First participant enrolled
August 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2009
CompletedAugust 7, 2007
August 1, 2007
July 16, 2007
August 6, 2007
Conditions
Keywords
Interventions
Eligibility Criteria
You may not qualify if:
- Patients with known allergies to chlorhexidine gluconate or any other ingredients in the product
- Patients with burns that include a high percentage of disrupted body surface area
- Use in patients undergoing lumbar punctures or contact with the meninges
- Patients with large open skin wounds; and
- Children less than 18 years old
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (7)
Northwestern Memorial Hospital
Chicago, Illinois, 60611, United States
University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242-1081, United States
Johns Hopkins Hospital
Baltimore, Maryland, 21205, United States
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
Barnes Jewish Hospital
St Louis, Missouri, 63110, United States
Memorial Sloan-Kettering Cancer Center
New York, New York, 10021, United States
Hunter Holmes McGuire Veteran Affairs Medical Center
Richmond, Virginia, 23249, United States
Related Publications (1)
Climo MW, Yokoe DS, Warren DK, Perl TM, Bolon M, Herwaldt LA, Weinstein RA, Sepkowitz KA, Jernigan JA, Sanogo K, Wong ES. Effect of daily chlorhexidine bathing on hospital-acquired infection. N Engl J Med. 2013 Feb 7;368(6):533-42. doi: 10.1056/NEJMoa1113849.
PMID: 23388005DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Michael W Climo, MD
Hunter Holmes Mcguire Veteran Affairs Medical Center
- PRINCIPAL INVESTIGATOR
Edward S Wong, MD
Hunter Holmes Mcguire Veteran Affairs Medical Center
- PRINCIPAL INVESTIGATOR
Jane A Cecil, MD
Hunter Holmes Mcguire Veteran Affairs Medical Center
- PRINCIPAL INVESTIGATOR
Kent Sepkowitz, MD
Weil Medical College of Cornell University
- PRINCIPAL INVESTIGATOR
Trish M Perl, MD, MSc
Johns Hopkins University
- PRINCIPAL INVESTIGATOR
Debbie Yokoe, MD, MPH
Harvard School of Medicine, Brigham and Women's Hospital
- PRINCIPAL INVESTIGATOR
Maureen Bolon, MD
Northwestern University Feinberg School of Medicine
- PRINCIPAL INVESTIGATOR
Dave K Warren, MD
Washington University School of Medicine
- PRINCIPAL INVESTIGATOR
Loreen Herwaldt, MD
University of Iowa
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- DEFINED POPULATION
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- FED
Study Record Dates
First Submitted
July 16, 2007
First Posted
July 17, 2007
Study Start
August 1, 2007
Study Completion
September 1, 2009
Last Updated
August 7, 2007
Record last verified: 2007-08