Gastrointestinal Evaluation in Young Men With Iron Deficiency Anemia

NCT00498511 | Unknown

• 1 other identifier: 64/07
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

Both upper gastrointestinal endoscopy and colonoscopy are recommended in men and post-menopausal women with iron deficiency anemia. Due to lack of data on the yield of these endoscopies in young men, they are currently investigated as older men. The aim of this study is to evaluate prospectively the prevalence of various gastrointestinal lesions in young men with iron deficiency anemia. Our hypothesis is that the diagnostic yield of colonoscopy in young anemic men without gastrointestinal symptoms is very low, especially if a potential lesion is detected during upper gastrointestinal endoscopy. Therefore, this study will try to identify predicting factors regarding the yield of both endoscopies. Another purpose is to evaluate the outcome of patients with negative endoscopic results, during a follow-up of two years.

Conditions

Anemia, Iron-Deficiency

Keywords

Anemia, Iron-Deficiency; Endoscopy, Gastrointestinal; Male, aged 18 to 40

Interventions

upper gastrointestinal endoscopy, colonoscopy PROCEDURE

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Men \< 40 years old of age with iron deficiency.
• hemoglobin level less than 13 gr/dl documented during the 2 years prior to entering the study with one of the following: 1) iron level less than 45 μg /dl and transferrin saturation less than 10%; 2) ferritin level less than 20 μg/L (both documented during the 4 months prior to entering the study).

You may not qualify if:

• Previously diagnosed disease that explain iron deficiency anemia
• Colonoscopy performed during the last 4 years
• Upper gastrointestinal endoscopy performed during the last 2 years

Sponsors & Collaborators

• Assaf-Harofeh Medical Center: lead

Study Sites (1)

Institute of Gastroenterology and Liver Diseases, Assaf harofeh Medical Center

Ẕerifin, 70300, Israel

Location

MeSH Terms

Conditions

Anemia, Iron-Deficiency

Interventions

Endoscopy, Digestive System; Colonoscopy

Condition Hierarchy (Ancestors)

Anemia, Hypochromic; Anemia; Hematologic Diseases; Hemic and Lymphatic Diseases; Iron Deficiencies; Iron Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, Digestive System; Diagnostic Techniques and Procedures; Diagnosis; Endoscopy; Diagnostic Techniques, Surgical; Digestive System Surgical Procedures; Surgical Procedures, Operative; Minimally Invasive Surgical Procedures; Endoscopy, Gastrointestinal

Study Officials

• Alain Nimrod Kimchi, M.D.

  Institute of Gastroenterology and Liver Diseases, Assaf-Harofeh Medical Center, 70300 Zerifin, Israel

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Alain Nimrod Kimchi, M.D.

CONTACT

972-08-9779722; nimrodk@asaf.health.gov.il

Efrat Broide, M.D.

CONTACT

972-08-9779793; efibroide@yahoo.com

Study Design

• Study Type: observational
• Observational Model: DEFINED POPULATION
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV

Study Record Dates

• First Submitted: July 8, 2007
• First Posted: July 10, 2007
• Study Start: August 1, 2007
• Last Updated: July 13, 2007

Record last verified: 2007-06

Locations

IL (1)