NCT00493727|Completed
Use of Mucomyst to Ameliorate Oxidant Stress in Diabetics With Proteinuria
Use of Mucomyst (NAC) to Ameliorate Oxidant Stress in Diabetic Patients as Measurable by Surrogate Serum Markers
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Use of Mucomyst (NAC) to Ameliorate Oxidant Stress in Diabetic Patients as Measurable by Surrogate Serum Markers
Sponsor study identifier
interventional
15
1 country
1
Study Start
September 2006
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2007
Actual (reported)Study Completion
December 2007
Actual (reported)The study will look at the effect of 30 days of treatment of 15 diabetics with proteinuria with N-acetylcysteine ( Mucomyst ) at a dose of 1 gm twice a day by mouth. The primary outcome that will be measured is change in the oxidant stress as measurable by changes in the serum level of isoprostane, Glutathione peroxidase, aconitase and Total oxidant stress. Secondary outcomes measured will be changes in proteinuria and kidney function as measured by spot urine pr/cr and estimated GFR by MDRD formula.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2007
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 2006
Date type not reportedThis date has not been verified as actual or estimated.
June 27, 2007
Actual (reported)June 28, 2007
Actual (reported)December 2007
Actual (reported)December 2007
Actual (reported)This research will test the possibility the Mucomyst given by mouth for a month will decrease oxidative stress and slow the disease.
Reduction of proteinuria
VA Medical Center, Dayton
Dayton, Ohio, 45428, United States
Mohammad G. Saklayen, MD
VA Medical Center, Dayton
15 participants (actual enrollment reported by the registry).
First Submitted
June 27, 2007
First Posted
June 28, 2007
Study Start
September 2006
Date type not reportedThis date has not been verified as actual or estimated.
N-acetylcysteine in Liver Transplantation
Contact the study team to confirm eligibility.
Primary Completion
December 2007
Actual (reported)Study Completion
December 2007
Actual (reported)Last Updated
May 19, 2008
Record last verified: 2008-05
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Source: ClinicalTrials.gov.
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