NCT00493168

Brief Summary

The first aim of this study is to determine how often unrecognized myocardial infarction occur in patients using a magnetic resonance imaging (MRI) technique (known as delayed enhancement MRI), as compared to the electrocardiogram. The second aim of this study is to determine the severity of coronary heart disease of the patients with unrecognized myocardial infarction. The final aim is to determine how the presence of unrecognized myocardial infarction detected by the MRI affects lifespan.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
185

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 1998

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1998

Completed
8.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2006

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

June 26, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 28, 2007

Completed
Last Updated

May 27, 2013

Status Verified

June 1, 2007

First QC Date

June 26, 2007

Last Update Submit

May 24, 2013

Conditions

Coronary ArteriosclerosisMyocardial Infarction

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with suspected coronary artery disease referred for invasive coronary angiography

You may not qualify if:

  • Clinical history of myocardial infarction
  • Percutaneous coronary intervention
  • Coronary artery bypass surgery
  • Known uncured malignancy
  • History of hypertrophic cardiomyopathy, myocarditis, or infiltrative heart disease
  • Contraindication of magnetic resonance imaging

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Northwestern University Medical School

Chicago, Illinois, 60611, United States

Location

Duke Cardiovascular Magnetic Resonance Center

Durham, North Carolina, 27710, United States

Location

Related Publications (1)

  • Kim HW, Klem I, Shah DJ, Wu E, Meyers SN, Parker MA, Crowley AL, Bonow RO, Judd RM, Kim RJ. Unrecognized non-Q-wave myocardial infarction: prevalence and prognostic significance in patients with suspected coronary disease. PLoS Med. 2009 Apr 21;6(4):e1000057. doi: 10.1371/journal.pmed.1000057. Epub 2009 Apr 21.

    PMID: 19381280DERIVED

MeSH Terms

Conditions

Coronary Artery DiseaseMyocardial Infarction

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Officials

  • Han W Kim, MD

    Duke Cardiovascular Magnetic Resonance Center

    PRINCIPAL INVESTIGATOR

  • Raymond J Kim, MD

    Duke Cardiovascular Magnetic Resonance Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 26, 2007

First Posted

June 28, 2007

Study Start

January 1, 1998

Study Completion

November 1, 2006

Last Updated

May 27, 2013

Record last verified: 2007-06

Locations

US(2)