The Long QT Syndrome in Pregnancy

NCT00488254 | Completed

• 1 other identifier: H06-03385
• Study Type: observational
• Target: 12
• Locations: 1 country
• Sites: 1

Brief Summary

Long QT Syndrome (LQTS) is a disease of young adults and can affect women of child bearing age. Suffers of LQTS are at risk of ventricular dysrhythmias including torsades de pointes and ventricular fibrillation. Pregnancy increases the chance that any mother may have an abnormal heart rhythm or arrhythmia. This chance is higher with the LQTS. There are only a few reported cases of women with the LQTS having a baby in the medical literature. This can make it difficult for the doctor caring for a pregnant woman with the long QT syndrome - especially should they need an anesthetic. We would like to study as many women who have had a baby who have the long QT syndrome to give us a better idea of whether there are any arrhythmias occurring at the time of delivery.

Conditions

Long QT Syndrome

Keywords

Long QT Syndrome; Romano Ward; Jervell-Lange Nielson Syndrome

Eligibility Criteria

• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Women managed at St. Paul's or BC Women's, Vancouver, who have been pregnant in the last 5 years

You may qualify if:

• Pregnant women with diagnoses of Long QT Syndrome, Romano Ward and Jervell - Lange Nielson Syndrome who delivered at BC Women's Hospital or St Paul's Hospital.

You may not qualify if:

• Non consent to participation in the study
• Age less than 19
• Non English speaker

Sponsors & Collaborators

• University of British Columbia: lead

Study Sites (1)

BC Women's Hospital

Vancouver, British Columbia, Canada

Location

MeSH Terms

Conditions

Long QT Syndrome; Jervell-Lange Nielsen Syndrome

Condition Hierarchy (Ancestors)

Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Cardiac Conduction System Disease; Heart Defects, Congenital; Cardiovascular Abnormalities; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Roanne Preston, MD

  University of British Columbia

  PRINCIPAL INVESTIGATOR

• Elizabeth Drake, MD

  University of British Columbia

  STUDY DIRECTOR

• Joanne Douglas, MD

  University of British Columbia

  STUDY DIRECTOR

• Marla Kiess, MD

  University of British Columbia

  STUDY DIRECTOR

• Stanley Tung, MD

  University of British Columbia

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: June 18, 2007
• First Posted: June 20, 2007
• Study Start: June 1, 2007
• Study Completion: April 1, 2008
• Last Updated: April 14, 2011

Record last verified: 2011-04

Locations

CA (1)