NCT00487565

Brief Summary

Prospective, multi-center clinical study to evaluate the clinical outcomes of the posterior stabilized design of the LCS® Complete Mobile-bearing Total Knee System

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
210

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2006

Longer than P75 for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2006

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

June 14, 2007

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 18, 2007

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2011

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

March 23, 2012

Completed
Last Updated

August 14, 2013

Status Verified

August 1, 2013

Enrollment Period

4.4 years

First QC Date

June 14, 2007

Results QC Date

February 21, 2012

Last Update Submit

August 6, 2013

Conditions

Keywords

Total knee replacementTotal knee arthroplastyOsteoarthritisRheumatoid or other inflammatory arthritisPost-traumatic or juvenile arthritis

Outcome Measures

Primary Outcomes (1)

  • Knee Active Flexion

    Active flexion is measured by how much a patient can bend their knee on their own, without assistance.

    12 month

Study Arms (1)

LCS Complete Posterior Stabilized knee implant

OTHER

Total knee arthroplasty with a posterior stabilized implant

Device: Total knee arthroplasty

Interventions

Total knee arthroplasty using a posterior stabilized implant

Also known as: LCS® Complete Posterior Stabilized Mobile-bearing Knee
LCS Complete Posterior Stabilized knee implant

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • M/F
  • Diagnosis of osteoarthritis, rheumatoid , post-traumatic, inflammatory, juvenile arthritis.
  • Skeletally mature, sufficient bone stock to seat and support prosthesis
  • Willing/able return for follow-up.
  • Subject is willing and able to provide informed patient consent for participation in the study

You may not qualify if:

  • History of recent/active joint sepsis, charcot neuropathy, psycho-social disorders, prior knee arthroplasty on affected site, metabolic disorders of calcified tissue
  • Communicable diseases that may limit follow-up
  • Medical-legal or workers compensation claims.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Colorado Joint Replacement

Denver, Colorado, 80210, United States

Location

Joint Reconstruction Center

Pittsburgh, Pennsylvania, 15260, United States

Location

Jordan-Young Institute

Virginia Beach, Virginia, 23462, United States

Location

Related Links

MeSH Terms

Conditions

OsteoarthritisArthritis, RheumatoidArthritis, Juvenile

Interventions

Arthroplasty, Replacement, Knee

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Intervention Hierarchy (Ancestors)

Arthroplasty, ReplacementArthroplastyOrthopedic ProceduresSurgical Procedures, OperativePlastic Surgery ProceduresProsthesis Implantation

Results Point of Contact

Title
Tammy O'Dell
Organization
DePuy Orthopaedics, Inc.

Study Officials

  • Tammy O'Dell, EMT, CCRA, CCRC

    DePuy

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
LTE60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 14, 2007

First Posted

June 18, 2007

Study Start

September 1, 2006

Primary Completion

February 1, 2011

Study Completion

February 1, 2011

Last Updated

August 14, 2013

Results First Posted

March 23, 2012

Record last verified: 2013-08

Locations