NCT00478556

Brief Summary

Patients who are scheduled by their health care provider for routine computed tomography (CT) scan will be asked to participate in this study. The primary purpose is to determine if there is a difference in patient preference for Omnipaque versus Gastroview as oral contrast for abdominal pelvic CT. A secondary objective is to evaluate if there is significant difference in bowel opacification for the two agents.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for phase_4 healthy

Timeline
Completed

Started Aug 2007

Typical duration for phase_4 healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 24, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 25, 2007

Completed
2 months until next milestone

Study Start

First participant enrolled

August 1, 2007

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2009

Completed
1.3 years until next milestone

Results Posted

Study results publicly available

June 11, 2010

Completed
Last Updated

April 18, 2017

Status Verified

March 1, 2017

Enrollment Period

1.6 years

First QC Date

May 24, 2007

Results QC Date

February 9, 2010

Last Update Submit

March 22, 2017

Conditions

Keywords

CT scanoral contrast

Outcome Measures

Primary Outcomes (1)

  • Preferred Contrast Agent

    The primary outcome variable is the taste test when subjects will be asked which preparation they prefer. Possible answers include Onmipaque, Gastroview or neither.

    1 Day

Secondary Outcomes (1)

  • Bowel Opacification Score

    Collected day of study

Study Arms (2)

1

ACTIVE COMPARATOR

Gastroview

Drug: Gastroview

2

EXPERIMENTAL

Omnipaque

Drug: Omnipaque

Interventions

Oral CT contrast

Also known as: Iohexol
2

Oral CT contrast

Also known as: diatrizoate meglumine and diatrizoate sodium solution USP
1

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients at least 19 years of age scheduled for outpatient contrast enhanced abdominal pelvic CT at The Kirklin Clinic in Birmingham Alabama as part of clinical care with the patient's provider will be screened for eligibility.

You may not qualify if:

  • Not competent to give consent.
  • Pregnant.
  • Known allergy to either of the contrast agents.
  • Loss of sense of taste or smell.
  • Contraindication to oral administration such as aspiration risk.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Kirklin Clinic

Birmingham, Alabama, 35249, United States

Location

MeSH Terms

Interventions

IohexolDiatrizoate Meglumine

Intervention Hierarchy (Ancestors)

Triiodobenzoic AcidsIodobenzoatesBenzoatesAcids, CarbocyclicCarboxylic AcidsOrganic ChemicalsBenzene DerivativesHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbonsMeglumineSorbitolSugar AlcoholsAlcoholsDiatrizoateHexosaminesAmino SugarsCarbohydrates

Limitations and Caveats

Study was completed.

Results Point of Contact

Title
Lisa Nelson
Organization
UAB Hospital Radiology

Study Officials

  • Michelle McNamara, MD

    University of Alabama at Birmingham

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 24, 2007

First Posted

May 25, 2007

Study Start

August 1, 2007

Primary Completion

March 1, 2009

Study Completion

March 1, 2009

Last Updated

April 18, 2017

Results First Posted

June 11, 2010

Record last verified: 2017-03

Locations