Study Stopped
Change in company strategy
Multi-marker INDex for the Risk Assessment of Sepsis in the Emergency departmenT (MINDSET)
MINDSET
Multi-marker Index for the Risk Assessment of Sepsis in the Emergency Department
2 other identifiers
observational
N/A
1 country
24
Brief Summary
The purpose of the study is to procure blood samples from patients ≥18 years of age who present to the Emergency Department (ED) with at least two of the diagnostic criteria for sepsis. Samples obtained upon enrollment will be used for future testing of the Triage Sepsis Panel and other biomarkers.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
Started May 2007
Shorter than P25 for all trials
24 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2007
CompletedFirst Submitted
Initial submission to the registry
May 10, 2007
CompletedFirst Posted
Study publicly available on registry
May 14, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2007
CompletedJuly 21, 2015
July 1, 2015
May 10, 2007
July 20, 2015
Conditions
Interventions
Eligibility Criteria
You may qualify if:
- Male or female 18 years of age or older
- Presenting to the emergency department (ED) for evaluation and who can be enrolled within 6 hours of initial ED evaluation
- Exhibiting two or more of any diagnostic criteria for sepsis
- Willing and able to comply with study procedures, including follow-up telephone contact (or in-house assessment) on Study Days 3, 14, and 28
You may not qualify if:
- Age \< 18 years
- Participation in any interventional clinical study within the previous 30 days
- Status-post cardiac arrest (within the past month)
- Moribund or with active "Do Not Resuscitate" or "Comfort Care Only" status
- Prisoners or other institutionalized or vulnerable individuals
- Already a hospital in-patient
- Unwilling or unlikely to comply with study procedures or to be reachable by telephone (or in person) for Day 3, 14, and 28 status assessments if discharged
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (24)
LA County/ USC
Los Angeles, California, United States
Olive View Medical Center - UCLA
Sylmar, California, United States
Denver Health
Denver, Colorado, United States
George Washington University
Washington D.C., District of Columbia, United States
Emory University
Atlanta, Georgia, United States
Northwestern University
Chicago, Illinois, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Brigham and Women's Hospital
Boston, Massachusetts, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
Bay State Medical Center
Springfield, Massachusetts, United States
Henry Ford Health System
Detroit, Michigan, United States
Wayne State - Detroit Receiving Hospital
Detroit, Michigan, United States
Cooper Health
Camden, New Jersey, United States
North Shore University Hospital
Manhasset, New York, United States
Staten Island University Hospital
Staten Island, New York, United States
SUNY Stony Brook
Stony Brook, New York, United States
Duke University Medical Center
Durham, North Carolina, United States
Wake Forest University
Winston-Salem, North Carolina, United States
Cleveland Clinic
Cleveland, Ohio, United States
Albert Einstein Medical Center
Philadelphia, Pennsylvania, United States
Temple University
Philadelphia, Pennsylvania, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Brown University
Providence, Rhode Island, United States
Virginia Commonwealth University Medical Center
Richmond, Virginia, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Emanuel Rivers, MD, MPH
Henry Ford Hospital
- PRINCIPAL INVESTIGATOR
Mitchell Levy, MD
Rhode Island Hospital
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
May 10, 2007
First Posted
May 14, 2007
Study Start
May 1, 2007
Study Completion
August 1, 2007
Last Updated
July 21, 2015
Record last verified: 2015-07