Usefulness of the Tsui Test in Combined Spinal-Epidural Analgesia in Labour
Can the Tsui Test be Used to Test the Placement of Epidural Catheters Following the Intrathecal Component of a Combined Spinal-epidural Technique Used for Labor Analgesia?
2 other identifiers
interventional
14
1 country
1
Brief Summary
Combined spinal epidural anesthesia (CSE) is a very effective technique to provide labor analgesia. One of the disadvantages of this technique is the delay in recognizing an error in the position of the epidural catheter because of the effects of the spinal component. Eventually in case of a misplaced catheter, the patient will experience pain or discomfort requiring a repeat procedure after the effect of drug given during the spinal wears off. Low current electrical stimulation test, or the Tsui test, has been used successfully to confirm catheter location in the epidural space. The investigators' objective in this study is to test the usefulness of the Tsui test to confirm the correct placement of the epidural catheter during CSE in laboring patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2007
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2007
CompletedFirst Submitted
Initial submission to the registry
April 23, 2007
CompletedFirst Posted
Study publicly available on registry
April 24, 2007
CompletedSeptember 5, 2011
September 1, 2011
28 days
April 23, 2007
September 2, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
change in current intensity required to produce a positive Tsui test after an intrathecal injection of bupivacaine
Within 2 hours of catheter placement
Study Arms (2)
1
EXPERIMENTALTsui test for combined spinal-epidural
2
EXPERIMENTALTsui test for intrathecal catheter
Interventions
0.7 mL of 0.25% isobaric bupivacaine and 15mcg of fentanyl
Eligibility Criteria
You may qualify if:
- American Society of Anesthesiologists (ASA) 1 or 2
- Full term pregnancy
- Patients requesting epidural in early labor
You may not qualify if:
- Any contraindication to regional anesthesia
- Allergy or hypersensitivity to lidocaine, bupivacaine, or fentanyl
- Received prior sedatives or opioids
- Abnormal vertebral anatomy
- Neurological disorders with lumbar involvement
- Patients with implanted electronic devices
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Mount Sinai Hospital
Toronto, Ontario, M5G 1X5, Canada
Related Publications (1)
Carvalho JC, Khemka R, Loke J, Tsui BC. Low-dose intrathecal local anesthetic does not increase the threshold current for the epidural stimulation test: a prospective observational trial of neuraxial analgesia in labouring women. Can J Anaesth. 2015 Mar;62(3):265-70. doi: 10.1007/s12630-014-0291-x. Epub 2014 Dec 11.
PMID: 25501494DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jose CA Carvalho, MD, PhD
MOUNT SINAI HOSPITAL
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 23, 2007
First Posted
April 24, 2007
Study Start
February 1, 2007
Primary Completion
March 1, 2007
Study Completion
March 1, 2007
Last Updated
September 5, 2011
Record last verified: 2011-09