Outcome After Multidisciplinary CO2 Laser Laparoscopic Excision of Deep Infiltrating Colorectal Endometriosis

NCT00461838 | Completed

• 1 other identifier: ML2818 - 22/10/2004
• Study Type: observational
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

Improved pain, sexuality and quality of life, high fertility and low complication and recurrence rates after multidisciplinary CO2 laser laparoscopic excision of deep infiltrating colorectal endometriosis.

Conditions

Endometriosis

Keywords

colorectal endometriosis; deep infiltrating endometriosis; dysmenorroe; dyspareunia; quality of life

Outcome Measures

Primary Outcomes (1)

• complication rate, cumulative recurrence and cumulative fertility rate, pain, quality of life and sexual satisfaction

  median follow-up: 29 months (range 6 - 76 months)

Study Arms (1)

1

All women (n=56) who had undergone CO2 laser laparoscopic radical excision of deep infiltrating endometriosis with active involvement of colorectal surgeon and/or urologist were selected retrospectively from the list of all patients (n=more than 2000) operated at the Leuven University Fertility Centre (LUFc) between September 1996 and July 2004.

Procedure: multidisciplinary laparoscopy; Other: Questionnaires

Interventions

multidisciplinary laparoscopy PROCEDURE

Multidisciplinary (with active involvement of the colorectal surgeon/urologist) fertility-sparing CO2 laser laparoscopic radical excision of deep infiltrating endometriosis.

1

Questionnaires OTHER

Patients (n=56) were asked to complete questionnaires regarding quality of life (QOL), pain, fertility and sexuality to compare their status before and after surgery, and their medical files were analyzed.

1

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All women (n=56) who had undergone CO2 laser laparoscopic radical excision of deep infiltrating endometriosis with active involvement of colorectal surgeon and/or urologist were selected retrospectively from the list of all patients (n=more than 2000) operated at the Leuven University Fertility Centre (LUFc) between September 1996 and July 2004.

You may qualify if:

• All women (n=56) who had undergone CO2 laser laparoscopic radical excision of deep infiltrating endometriosis with active involvement of colorectal surgeon and/or urologist
• operated at the Leuven University Fertility Centre (LUFc) between September 1996 and July 2004

You may not qualify if:

• Women who had undergone CO2 laser laparoscopic excision of deep infiltrating endometriosis without active involvement of colorectal surgeon and/or urologist

Sponsors & Collaborators

• University Hospital, Gasthuisberg: lead

Study Sites (1)

University Hospital Gasthuisberg

Leuven, 3000, Belgium

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

Endometriosis was proven by histologic examination of excised lesions.

MeSH Terms

Conditions

Endometriosis; Dyspareunia

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Genital Diseases, Male; Sexual Dysfunction, Physiological; Male Urogenital Diseases; Sexual Dysfunctions, Psychological; Mental Disorders

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Christel LC Meuleman, MD

  University Hospital Gasthuisberg, Catholic University, Leuven, Belgium

  PRINCIPAL INVESTIGATOR

• Thomas D'Hooghe, MD, PhD

  University Hospital Gasthuisberg, Catholic University, Leuven, Belgium

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: April 17, 2007
• First Posted: April 18, 2007
• Study Start: September 1, 1996
• Primary Completion: July 1, 2004
• Study Completion: July 1, 2004
• Last Updated: February 20, 2009

Record last verified: 2009-02

Locations

BE (1)