NCT00457535

Brief Summary

Responsiveness of recombinant human erythropoietin (rHuEPO) is known to be related with body fatness in hemodialysis (HD) patients. Adiponectin (ADPN) is inversely associated with body fat mass, and in healthy subjects, low ADPN is a predictor of mortality. Recently, higher rHuEPO dose itself is demonstrated to be associated with poor prognosis. So, in this study, we prospectively examined the relationship between rHuEPO dose, serum ADPN, and mortality in patients beginning HD.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Aug 2000

Longer than P75 for all trials

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2000

Completed
3.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2004

Completed
2.8 years until next milestone

First Submitted

Initial submission to the registry

April 5, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 6, 2007

Completed
Last Updated

April 6, 2007

Status Verified

April 1, 2007

First QC Date

April 5, 2007

Last Update Submit

April 5, 2007

Conditions

Renal Dialysis

Keywords

recombinant human erythropoietinadiponectinmortality

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • patients who had first started hemodialysis therapy from August 2000 to May 2001 in 11 dialysis centers in Shizuoka prefecture area.

You may not qualify if:

  • nothing particular

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Naro Ohashi, MD,PhD

    First Department of Medicine, Hamamatsu University School of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
DEFINED POPULATION
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

April 5, 2007

First Posted

April 6, 2007

Study Start

August 1, 2000

Study Completion

July 1, 2004

Last Updated

April 6, 2007

Record last verified: 2007-04