Application of Capnography Monitoring on the General Care Nursing Unit

NCT00457080 | Completed DMC

• 1 other identifier: CAPNO-P806
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to increase the detection of undiagnosed obstructive sleep apnea (OSA) and secondly to increase the sensitivity for detection of respiratory depression (\< 6 breaths per minute) in post operative patients on the general care nursing unit.

Conditions

Postoperative Complications

Keywords

capnography; safety; opioids; respiratory depression; postoperative; orthopedic; OSA; apnea

Outcome Measures

Primary Outcomes (1)

• Increase the detection of undiagnosed obstructive sleep apnea (OSA)

Secondary Outcomes (1)

• Increase the sensitivity for detection of respiratory depression (< 6 breaths per minute) in post operative patients on the general care nursing unit

Interventions

Alaris ETCO2 monitor - cont. resp. rate, & apnea events DEVICE

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Orthopedic surgical procedure
• Respiration rate \< 10 breaths per minute requiring supplement oxygen
• One of the following:
• body mass index \>30
• history of snoring
• basal rate of opioid, and
• one event of RR \<10 in the post anesthesia care unit.

You may not qualify if:

• COPD
• \< 18 y/o
• A diagnosis of obstructive sleep apnea.

Sponsors & Collaborators

• Texas Health Resources: lead

Study Sites (1)

Presbyterian Hospital of Dallas

Dallas, Texas, 75231, United States

Location

Related Publications (13)

• Hutchison R. Capnography monitoring during opioid PCA administration. J Opioid Manag. 2006 Jul-Aug;2(4):207-8. doi: 10.5055/jom.2006.0032. No abstract available.

  PMID: 17319481 BACKGROUND

• Kirk VG, Batuyong ED, Bohn SG. Transcutaneous carbon dioxide monitoring and capnography during pediatric polysomnography. Sleep. 2006 Dec;29(12):1601-8. doi: 10.1093/sleep/29.12.1601.

  PMID: 17252891 BACKGROUND

• Krauss B, Hess DR. Capnography for procedural sedation and analgesia in the emergency department. Ann Emerg Med. 2007 Aug;50(2):172-81. doi: 10.1016/j.annemergmed.2006.10.016. Epub 2007 Jan 12.

  PMID: 17222941 BACKGROUND

• Anderson JL, Junkins E, Pribble C, Guenther E. Capnography and depth of sedation during propofol sedation in children. Ann Emerg Med. 2007 Jan;49(1):9-13. doi: 10.1016/j.annemergmed.2006.06.011. Epub 2006 Aug 17.

  PMID: 17141136 BACKGROUND

• Lightdale JR, Goldmann DA, Feldman HA, Newburg AR, DiNardo JA, Fox VL. Microstream capnography improves patient monitoring during moderate sedation: a randomized, controlled trial. Pediatrics. 2006 Jun;117(6):e1170-8. doi: 10.1542/peds.2005-1709. Epub 2006 May 15.

  PMID: 16702250 BACKGROUND

• Anderson MR. Capnography: considerations for its use in the emergency department. J Emerg Nurs. 2006 Apr;32(2):149-53. doi: 10.1016/j.jen.2005.12.025. No abstract available.

  PMID: 16580478 BACKGROUND

• Corbo J, Bijur P, Lahn M, Gallagher EJ. Concordance between capnography and arterial blood gas measurements of carbon dioxide in acute asthma. Ann Emerg Med. 2005 Oct;46(4):323-7. doi: 10.1016/j.annemergmed.2004.12.005.

  PMID: 16187465 BACKGROUND

• Verschuren F, Heinonen E, Clause D, Zech F, Reynaert MS, Liistro G. Volumetric capnography: reliability and reproducibility in spontaneously breathing patients. Clin Physiol Funct Imaging. 2005 Sep;25(5):275-80. doi: 10.1111/j.1475-097X.2005.00620.x.

  PMID: 16117730 BACKGROUND

• Fisher QA. Can capnography substitute for auscultation in sedation cases? Anesth Analg. 2005 May;100(5):1546. doi: 10.1213/01.ANE.0000151470.50760.4A. No abstract available.

  PMID: 15845739 BACKGROUND

• Hatlestad D. Capnography in sedation and pain management. Emerg Med Serv. 2005 Mar;34(3):65-9.

  PMID: 15839539 BACKGROUND

• Eisenbacher S, Heard L. Capnography in the gastroenterology lab. Gastroenterol Nurs. 2005 Mar-Apr;28(2):99-105; quiz 105-6. doi: 10.1097/00001610-200503000-00003.

  PMID: 15832109 BACKGROUND

• Dziewas R, Hopmann B, Humpert M, Bontert M, Dittrich R, Ludemann P, Young P, Ringelstein EB, Nabavi DG. Capnography screening for sleep apnea in patients with acute stroke. Neurol Res. 2005 Jan;27(1):83-7. doi: 10.1179/016164105X18359.

  PMID: 15829165 BACKGROUND

• Engoren M, Plewa M, O'Hara D, Kline JA. Evaluation of capnography using a genetic algorithm to predict PaCO2. Chest. 2005 Feb;127(2):579-84. doi: 10.1378/chest.127.2.579.

  PMID: 15705999 BACKGROUND

MeSH Terms

Conditions

Postoperative Complications; Respiratory Insufficiency; Apnea

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiration Disorders; Respiratory Tract Diseases; Signs and Symptoms, Respiratory; Signs and Symptoms

Study Officials

• Rob W Hutchison

  Texas Health Resources

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: April 3, 2007
• First Posted: April 5, 2007
• Study Start: October 1, 2006
• Study Completion: February 1, 2007
• Last Updated: July 9, 2008

Record last verified: 2008-07

Locations

US (1)