NCT00456469|UnknownDMC
Diagnosis of Active and Latent TB Infection With IFN-y Assays in African Children
ALTAC
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ALTAC
Sponsor study identifier
observational
500
1 country
1
Study Start
May 2007
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
October 2009
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study based in Southern Ethiopia Purpose - to explore if children in contact with adults with TB have positive acute reactants such as IFN-y and other cytokine responses; if these responses discriminate between high and low risk of disease progression and whether these could be incorporated into improved diagnostic approaches.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
October 2009
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
April 4, 2007
Actual (reported)April 5, 2007
Actual (reported)May 2007
Date type not reportedThis date has not been verified as actual or estimated.
October 2009
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Bushullo Major Health Centre
Awasa, Southern Region, 12, Ethiopia
Yassin MA, Petrucci R, Garie KT, Harper G, Teshome A, Arbide I, Asnake G, Ahmed HJ, Mammo T, Yesuf K, Cuevas LE. Use of tuberculin skin test, IFN-gamma release assays and IFN-gamma-induced protein-10 to identify children with TB infection. Eur Respir J. 2013 Mar;41(3):644-8. doi: 10.1183/09031936.00012212. Epub 2012 Sep 20.
Garie KT, Yassin MA, Cuevas LE. Lack of adherence to isoniazid chemoprophylaxis in children in contact with adults with tuberculosis in Southern Ethiopia. PLoS One. 2011;6(11):e26452. doi: 10.1371/journal.pone.0026452. Epub 2011 Nov 1.
Luis Cuevas, Dr
Liverpool School of Tropical Medicine
First Submitted
April 4, 2007
First Posted
April 5, 2007
Study Start
May 2007
Date type not reportedThis date has not been verified as actual or estimated.
Study Completion
October 2009
Estimated (date passed)A Home-Based Approach to Tuberculosis Preventive Treatment Management
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Yassin MA, Petrucci R, Garie KT, Harper G, Arbide I, Aschalew M, Merid Y, Kebede Z, Bawazir AA, Abuamer NM, Cuevas LE. Can interferon-gamma or interferon-gamma-induced-protein-10 differentiate tuberculosis infection and disease in children of high endemic areas? PLoS One. 2011;6(9):e23733. doi: 10.1371/journal.pone.0023733. Epub 2011 Sep 23.
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
April 5, 2007
Record last verified: 2007-04
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