NCT00456404

Brief Summary

To evaluate the effectiveness of a topical preparation of peppermint water in comparison with that of expressed breast milk for the prevention of nipple cracks in primiparous breastfeeding women.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
196

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2005

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2005

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2005

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

April 4, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 5, 2007

Completed
Last Updated

April 5, 2007

Status Verified

March 1, 2004

First QC Date

April 4, 2007

Last Update Submit

April 4, 2007

Conditions

Keywords

peppermint waternipple cracklactating women

Outcome Measures

Primary Outcomes (2)

  • The primary outcome that the study was designed to evaluate: the presence and severity of sore nipples, nipple pain.

  • The time at which the outcome is measured: nipple and areola cracks, and pain at days 4, 8, 14.

Secondary Outcomes (1)

  • The frequency and duration of breastfeeding at days 4, 8, 14 and the number of mothers who continued feeding at week 6 was used as the secondary outcome

Interventions

Eligibility Criteria

Age14 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • New mothers with healthy term infants (38 weeks gestation or more) are eligible for recruitment into the study. The sample of breastfeeding mothers were collected in two cohorts according delivery type. Each group consisted of 98 primipara mothers.

You may not qualify if:

  • Mothers who didn't plan to use peppermint water
  • Discharged before an interview or had preterm delivery
  • Postpartum fever
  • Breast infection
  • Nipple abnormalities
  • Age less than 18 years
  • Twins
  • Taking medications at night
  • Mothers who didn't have telephone line, and who were illiterate.
  • Infants who used bottle-feeding or pacifier, or who had mouth infection, or an abnormal short frenulum.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Breast Diseases

Condition Hierarchy (Ancestors)

Skin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Manizheh Sayyah Melli, MD

    Tabriz University of Medical Sciences

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

April 4, 2007

First Posted

April 5, 2007

Study Start

February 1, 2005

Study Completion

June 1, 2005

Last Updated

April 5, 2007

Record last verified: 2004-03