Pulmonary Function Changes in 10 Pack Year Smokers With Chronic Bronchitis

NCT00454675 | Completed

• 1 other identifier: COPD-2006-01
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

To determine whether an average population of males and females who smoke 10 pack years or more of cigarettes in a primary care setting with chronic bronchitis has already developed significant changes on pulmonary function testing.

Conditions

Chronic Bronchitis; COPD

Keywords

Smokers; Chronic Bronchitis; Pulmonary Function Test Abnormalities; COPD

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Primary care

You may qualify if:

• Subjects must sign a written informed consent.
• Enrollment population would include males and females 40 years of age to 80 years of age.
• Current history or past history of smoking at least 10 pack years of cigarettes.
• Patients to satisfy the diagnosis of chronic bronchitis.
• Non-smokers will be allowed in the control group

You may not qualify if:

• Chronic infections such as TB or other infections of the lungs.
• Collagen diseases such as rheumatoid arthritis or lupus which affect the lungs.
• Any previous lung diseases such as pneumoconiosis.
• Previous accidents or surgery which would involve the lungs or the ribcage.
• Maintenance medications used for asthma or COPD such as long acting bronchodilators or inhaled corticosteroids.
• Asthma patients or other patients with allergies that may affect pulmonary function test will be excluded.
• Any medical condition in the opinion of the investigator that would make the subject unsuitable for enrollment.
• Pregnant woman will not be allowed
• Current participation in a research study or within the last 30 days.

Sponsors & Collaborators

• Westside Family Medical Center, P.C.: lead
• GlaxoSmithKline: collaborator

Study Sites (1)

Westside Family Medical Center, P.C.

Kalamazoo, Michigan, 49009, United States

Location

MeSH Terms

Conditions

Bronchitis, Chronic; Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Bronchitis; Respiratory Tract Infections; Infections; Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Gary E Ruoff, MD

  Westside Family Medical Center, P.C.

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: March 30, 2007
• First Posted: April 2, 2007
• Study Start: March 1, 2007
• Study Completion: August 1, 2008
• Last Updated: August 15, 2008

Record last verified: 2008-06

Locations

US (1)