NCT00451425

Brief Summary

Excessive weight gain during pregnancy is associated with complications during delivery primarily due to macrosomia (large babies) but also with high levels of weight retention post pregnancy and thereby increased risk of future weight related health problems. The primary aim of this study is to evaluate the efficacy of an intervention consisting of; recurrent Motivational Interviewing (MI), prescription of physical activity and extended information on recommended weight gain during pregnancy in regards to preventing excessive gestational weight gain.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
430

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2007

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 21, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 23, 2007

Completed
1 month until next milestone

Study Start

First participant enrolled

May 1, 2007

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2010

Completed
Last Updated

May 29, 2009

Status Verified

May 1, 2009

Enrollment Period

2.6 years

First QC Date

March 21, 2007

Last Update Submit

May 28, 2009

Conditions

Keywords

pregnancyweight gainobesitymacrosomia

Outcome Measures

Primary Outcomes (1)

  • The number of women with a weight gain during pregnancy within IOM´s recommendation is compared between study groups.

    9 months

Secondary Outcomes (4)

  • Weight retention(kg) up until one year after delivery is compared between study groups.

    one year after delivery

  • Number of fetal and maternal complications in pregnancy is compared between study groups

    9 months

  • Number of fetal and maternal complications during delivery is compared between study groups

    during delivery

  • Child birth weight and weight development of the child up to one year of age is compared between study groups.

    one year

Study Arms (1)

control

NO INTERVENTION

standard maternity care

Behavioral: motivational intervention in pregnancy

Interventions

Motivational program including individualized counseling on diet and physical activity

control

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \>18 years,
  • Adequate language skills (swedish),
  • BMI\>19.9,
  • Pregnancy estimated \<16 weeks (LMP),
  • Planned for basic pregnancy surveillance (healthy mother).

You may not qualify if:

  • History of eating disorder,
  • History of having a growth restricted child.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Modrahalsovarden Orebro lan

Örebro, Sweden

RECRUITING

Related Publications (1)

  • Ronnberg AK, Ostlund I, Fadl H, Gottvall T, Nilsson K. Intervention during pregnancy to reduce excessive gestational weight gain-a randomised controlled trial. BJOG. 2015 Mar;122(4):537-44. doi: 10.1111/1471-0528.13131. Epub 2014 Nov 4.

MeSH Terms

Conditions

Weight GainObesity

Interventions

Pregnancy

Condition Hierarchy (Ancestors)

Body Weight ChangesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsOverweightOvernutritionNutrition DisordersNutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

ReproductionReproductive Physiological PhenomenaReproductive and Urinary Physiological Phenomena

Study Officials

  • Kerstin Nilsson, MD. MD

    Region Örebro County

    STUDY CHAIR

Central Study Contacts

AnnKristin M Ronnberg, MD

CONTACT

Kerstin Nilsson, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

March 21, 2007

First Posted

March 23, 2007

Study Start

May 1, 2007

Primary Completion

December 1, 2009

Study Completion

October 1, 2010

Last Updated

May 29, 2009

Record last verified: 2009-05

Locations