NCT00451087

Brief Summary

We assume the etiology of patellofemoral pain syndrome is related to mechanical properties of tendon structures of the vastus medialis obliquus and vastus lateralis. Consequently, we will measure the electromechanical delay and some viscoelastic parameters of the two muscles. Besides, we will also investigate the effects of exercise training to the mechanical properties of the muscles.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Dec 2006

Typical duration for phase_1

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2006

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2007

Completed
21 days until next milestone

First Submitted

Initial submission to the registry

March 22, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 23, 2007

Completed
2.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2009

Completed
Last Updated

January 30, 2008

Status Verified

December 1, 2006

Enrollment Period

3 months

First QC Date

March 22, 2007

Last Update Submit

January 28, 2008

Conditions

Patellofemoral Pain Syndrome

Keywords

mechanical propertieselectromechanical delayviscoelasticityVMOpatellofemoral pain syndrome

Outcome Measures

Primary Outcomes (1)

  • electromechanical delay

    minisecond

Secondary Outcomes (2)

  • quadriceps muscle force

    second

  • the displacement of deep aponeurosis of vasti muscles

    second

Study Arms (2)

1

EXPERIMENTAL
Procedure: leg press training

2

ACTIVE COMPARATOR
Procedure: isokinetic training

Interventions

leg press trainingPROCEDURE

quadriceps muscle strengthening. 30min/ 3times/ week

1
isokinetic trainingPROCEDURE

quadriceps muscle training. 30 min/ 3 times/ week

2

Eligibility Criteria

AgeUp to 49 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Below 50 years old.
  • Subjects have at least two of five conditions of knee pain: to squat down, to go or down stairs, to keep prolong sitting position, to be palpated the joint cartilage of patella, to be test by Clark sign.
  • Subjects have the symptoms for 3 months at least.

You may not qualify if:

  • Subjects have the other knee disorder in addition to PFPS.
  • Subjects had ever received operations of knee in past 3 months.
  • Subjects have neurological disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kinesiology Laboratory

Taipei, 100, Taiwan

RECRUITING

Related Publications (3)

  • Cowan SM, Hodges PW, Bennell KL, Crossley KM. Altered vastii recruitment when people with patellofemoral pain syndrome complete a postural task. Arch Phys Med Rehabil. 2002 Jul;83(7):989-95. doi: 10.1053/apmr.2002.33234.

    PMID: 12098160BACKGROUND

  • Kubo K, Kanehisa H, Kawakami Y, Fukunaga T. Elastic properties of muscle-tendon complex in long-distance runners. Eur J Appl Physiol. 2000 Feb;81(3):181-7. doi: 10.1007/s004210050028.

    PMID: 10638375RESULT

  • Chen HY, Chien CC, Wu SK, Liau JJ, Jan MH. Electromechanical delay of the vastus medialis obliquus and vastus lateralis in individuals with patellofemoral pain syndrome. J Orthop Sports Phys Ther. 2012 Sep;42(9):791-6. doi: 10.2519/jospt.2012.3973. Epub 2012 Aug 2.

    PMID: 22951377DERIVED

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal Diseases

Study Officials

  • Mei-Hwa Jan, Master

    School and Graduate Institude of Physical Therapy,NTU

    STUDY DIRECTOR

Central Study Contacts

Mei-Hwa Jan, Master

CONTACT

886-2-33228138mhjan@ntu.edu.tw

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

March 22, 2007

First Posted

March 23, 2007

Study Start

December 1, 2006

Primary Completion

March 1, 2007

Study Completion

September 1, 2009

Last Updated

January 30, 2008

Record last verified: 2006-12

Locations

TW(1)