NCT00447850

Brief Summary

Previous studies have suggested that premature luteinization (PL)during controlled ovarian stimulation (COS) decreases the implantation rate due to a negative effect on the endometrium receptivity. This study aims to describe the impact on endometrial gene expression of PL in GnRH antagonist and GnRH agonist cycles.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Apr 2007

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 13, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 15, 2007

Completed
17 days until next milestone

Study Start

First participant enrolled

April 1, 2007

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2009

Completed
Last Updated

September 21, 2009

Status Verified

September 1, 2009

Enrollment Period

2.3 years

First QC Date

March 13, 2007

Last Update Submit

September 18, 2009

Conditions

Premature Luteinization

Interventions

endometrial biopsyPROCEDURE

Eligibility Criteria

Age18 Years - 35 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Oocyte donors
  • Age between 18-35 years old
  • BMI 18-29
  • NORMOGONADOTROPHICS
  • PROGESTERONE ≥ 1.2 ng/ml on hCG day

You may not qualify if:

  • PolyCystic Ovarian Syndrome (PCOS)
  • Endometriosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ivi Valencia

Valencia, 46015, Spain

Location

Study Officials

  • Elena Labarta, MD

    Instituto Valenciano de la Infertilidad

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Sponsor Type
OTHER

Study Record Dates

First Submitted

March 13, 2007

First Posted

March 15, 2007

Study Start

April 1, 2007

Primary Completion

July 1, 2009

Study Completion

July 1, 2009

Last Updated

September 21, 2009

Record last verified: 2009-09

Locations

ES(1)