NCT00446498

CompletedPhase 4

CPAP Versus NPPV in ACPE

Ospedale S. Giovanni Bosco Source

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Other study identifiers

Sponsor study identifier

gbosco1

Study Type

interventional

Reported enrollment (type unavailable)

80

Locations

1 country

Sites

1

Timeline

Study Start

July 2002

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

Not reported

Date not reported

Study Completion

May 2005

Actual (reported)

Brief Summary

To assess the intubation rate in patients affected by severe cardiogenic pulmonary edema treated with CPAP or NPPV.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Reported enrollment (type unavailable): 80 participants
Study completion date: May 2005
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
July 2002
Date type not reported
This date has not been verified as actual or estimated.
Study Completion
May 2005
Actual (reported)
First Submitted
March 12, 2007
Actual (reported)
First Posted
March 13, 2007
Actual (reported)

Last Updated: April 3, 2007
Status Verified: April 2007
Last Update Submitted: April 2, 2007

Conditions

Pulmonary Edema

Outcome Measures

Primary Outcomes (1)

Intubation rate

Secondary Outcomes (3)

time of recovery
hospital length of stay
mortality and improvement in gas exchange

Interventions

CPAP and Non Invasive VentilationDevice

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

rapid onset of the symptoms
severe dyspnoea at rest

Sponsors & Collaborators

Ospedale S. Giovanni Bosco
Otherlead

Study Sites (1)

Ospedale San Giovanni Bosco Medicina d'Urgenza

Torino, 10154, Italy

MeSH Terms

Conditions

Pulmonary Edema

Interventions

Continuous Positive Airway PressureNoninvasive Ventilation

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Positive-Pressure RespirationRespiration, ArtificialAirway ManagementTherapeuticsRespiratory Therapy

Study Officials

Giovanni Ferrari, MD
Ospedale San Giovanni Bosco ASL4
PRINCIPAL INVESTIGATOR
Giovanni Ferrari, MD
Ospedale San Giovanni Bosco ASL4 Torino Italy
PRINCIPAL INVESTIGATOR

Study Design

Study Type: interventional
Phase: phase 4
Allocation: RANDOMIZED
Masking: NONE
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER

Study Record Dates

First Submitted

March 12, 2007

First Posted

March 13, 2007

Study Start

July 2002

Date type not reported

This date has not been verified as actual or estimated.

Study Completion

May 2005

Actual (reported)

Lung Ultrasound in High Altitude Lung Edema

Completed

NCT02655094

Unilateral Pulmonary Edema After Minimal-invasive Mitral Valve Surgery

Completed

NCT05095974

Predictors of Pulmonary Edema in Severe Preeclampsia

Unknown

NCT03942055

The Association of B-7 Lung Ultrasound Pattern With the Development of Postoperative Pulmonary Edema

Withdrawn

NCT05049889

Screening for Individual Susceptibility Factors to Immersion Pulmonary Edema

Not ApplicableUnknown

NCT06107465

High Versus Low Dose Nitroglycerin in Acute Pulmonary Edema

Phase 2/3Unknown

respiratory rate \> 30 breath per minute

use of accessory respiratory muscles

PaO2/FiO2 \< 200, radiological findings of ACPE

You may not qualify if:

ST elevation myocardial infarction
hemodynamic instability (systolic arterial pressure \< 90 mmHg
need for immediate endotracheal intubation (respiratory arrest, bradypnea
inability to protect the airways, impaired sensorium (agitation or unconsciousness
inability to clear secretions, respiratory tract infections
chronic obstructive pulmonary disease (COPD) exacerbation, chronic respiratory failure necessitating long-term oxygen therapy
pulmonary embolism, pneumonia, recent oesophageal-gastric surgery
gastrointestinal bleeding
facial deformities
haematological malignancy or cancer with Eastern Cooperative Oncology Group (ECOG) performance status ≥ 2.

Contact the study team to confirm eligibility.

Last Updated

April 3, 2007

Record last verified: 2007-04

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

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Registry identifier: NCT00446498
Data provider: ClinicalTrials.gov
Source updated: 2007-04-03
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:25:30 UTC

Locations

IT(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations