Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome

NCT00445224 | Completed Results

• 1 other identifier: 07-0138-F2L
• Study Type: interventional
• Target: 33
• Locations: 1 country
• Sites: 1

Brief Summary

Patellofemoral pain syndrome (PFPS) is a common knee disorder affecting physically active people. Despite the growing base of support for the early introduction of hip strengthening exercises into the rehabilitation of PFPS, there have been few randomized clinical trials comparing isolated hip to isolated quadriceps strengthening. The purpose of this study is to determine how different exercises affect pain, strength, muscle activity, and function in female subjects with patellofemoral pain. The researchers hypothesize that females diagnosed with PFPS who initially participate in a hip strengthening program will report a greater perceived level of function, greater strength, less pain, and improved neuromuscular activity than those who participate in a progressive quadriceps strengthening intervention.

Conditions

Patellofemoral Pain Syndrome

Keywords

Knee pain; Rehabilitation

Outcome Measures

Primary Outcomes (3)

• Visual Analog Pain Scale (Describing Worst Pain Felt During the Past Week)

  0 to 10 cm line with 0 representing no pain and 10 representing severe pain

  weekly

• Subjective Function by Lower Extremity Functional Scale Report Form

  Baseline, Mid-Intervention, and Post-Intervention

• Visual Analog Pain Scale

  Visual analog pain scale at end of intervention. 0 to 10 cm line with 0 representing no pain and 10 representing severe pain

  8 week

Secondary Outcomes (4)

• Strength by Isometric Dynamometer

  Baseline, Mid, and Post-Intervention

• Neuromuscular Activity by Surface Electromyographical Amplitude During Stair Descent

  Baseline, Mid and Post-Intervention

• Objective Function by Step-down Task for 30 Seconds

  Baseline, Mid, and Post-Intervention

• Hip Abduction Strength

  8 week

Study Arms (2)

Hip Progressive Resistive Exercises

EXPERIMENTAL

Exercises targeting hip musculature such as hip abduction and hip external rotation that was progressed by increased resistance following typical progressive resistive exercise approach.

Other: Hip Progressive Resistive Exercise

Quad Progressive Resistive Exercises

ACTIVE COMPARATOR

Exercises targeting quadriceps musculature such as quadriceps isometric setting, terminal knee extensions, and straight leg raises that was progressed by increased resistance following typical progressive resistive exercise approach..

Other: Quad Progressive Resistive Exercises

Interventions

Hip Progressive Resistive Exercise OTHER

Hip Progressive Resistance Exercise program will be carried out by subjects under supervision once a week and then performed at home 2 additional times at home without supervision. Exercises focus on strengthening hip abduction ad external rotation musculature.

Hip Progressive Resistive Exercises

Quad Progressive Resistive Exercises OTHER

Quad Progressive Resistive Exercise program will be carried out by subjects under supervision once a week and then performed at home 2 additional times at home without supervision. Exercises focus on strengthening quadriceps musculature with straight leg raises and quadriceps isometrics.

Quad Progressive Resistive Exercises

Eligibility Criteria

• Age: 15 Years - 35 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• anterior or retropatellar knee pain reported during at least 2 of the following activities: ascending and descending stairs, hopping and running, squatting, kneeling, and prolonged sitting
• insidious onset of symptoms not related to trauma
• pain with compression of the patella
• pain on palpation of the patellar facets

You may not qualify if:

• symptoms present for less than one month
• clinical evidence of other knee pathology
• history of recent knee surgery within past one year
• history of patellar dislocations or subluxations
• current significant injury affecting other lower extremity joints

Sponsors & Collaborators

• Timothy Uhl: lead

Study Sites (1)

University of Kentucky

Lexington, Kentucky, 40506, United States

Location

Related Publications (1)

• Dolak KL, Silkman C, Medina McKeon J, Hosey RG, Lattermann C, Uhl TL. Hip strengthening prior to functional exercises reduces pain sooner than quadriceps strengthening in females with patellofemoral pain syndrome: a randomized clinical trial. J Orthop Sports Phys Ther. 2011 Aug;41(8):560-70. doi: 10.2519/jospt.2011.3499. Epub 2011 Jun 7.

  PMID: 21654093 DERIVED

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases

Limitations and Caveats

Early termination leading to small number of subjects analyzed. Intention to treat analysis, last score carried forward, was used to analyze all outcome data.

Results Point of Contact

• Title: Dr. Tim L. Uhl Principal Investigator
• Organization: University of Kentucky

tluhl2@uky.edu

859-323-1100

Study Officials

• Timothy Uhl, PhD, ATC, PT

  University of Kentucky

  STUDY CHAIR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: March 6, 2007
• First Posted: March 8, 2007
• Study Start: January 1, 2008
• Primary Completion: January 1, 2010
• Study Completion: January 1, 2010
• Last Updated: March 28, 2017
• Results First Posted: August 5, 2010

Record last verified: 2017-02

Locations

US (1)