NCT00443859

Terminated

N-Terminal Pro-brain Natriuretic Peptide Hormone and Persist...

Christiana Care Health Services Source

Christiana Care Health Services

ClinicalTrials.gov

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Other study identifiers

Sponsor study identifier

CCC 27004

Study Type

observational

Actual enrollment (reported)

10

Locations

1 country

Sites

2

Timeline

Study Start

February 2007

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

September 2008

Actual (reported)

Study Completion

September 2008

Actual (reported)

Brief Summary

Babies who are suspected of having persistent pulmonary hypertension (PPHN) will be included in this study. PPHN is a condition in which the blood is restricted from flowing to the lungs in a normal way making it hard for babies to breath and placing strain on the heart. This study will observe whether certain hormones that measure stress (N-terminal pro-brain natriuretic peptide) can help determine how well a baby will do when they have PPHN.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: terminated
Actual enrollment (reported): 10 participants
Study completion date: September 2008
Actual (reported)
Listed locations: 1 countries · 2 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
February 2007
Date type not reported
This date has not been verified as actual or estimated.
First Submitted
March 2, 2007
Actual (reported)
First Posted
March 6, 2007
Actual (reported)
Primary Completion
September 2008
Actual (reported)
Study Completion
September 2008
Actual (reported)

Last Updated: July 11, 2016
Status Verified: May 2009
Last Update Submitted: July 7, 2016

Conditions

Persistent Pulmonary Hypertension of Newborn

Keywords

Persistent Pulmonary HypertensionN-terminal pro brain natriuretic peptide

Study Arms (1)

PPHN

Infants with persistent pulmonary hypertension (PPHN)

Eligibility Criteria

AgeUp to 6 Months

Sexall

Healthy VolunteersYes

Age GroupsChild (0-17)

Sampling MethodNon-Probability Sample

Study Population

All infants who are admitted to the NICU with a diagnoses of PPHN.

You may qualify if:

\>/= 34 weeks gestation at birth

Sponsors & Collaborators

Thomas Jefferson University
Othercollaborator
Christiana Care Health Services
Otherlead

Study Sites (2)

Christiana Hospital

Newark, Delaware, 19718, United States

Thomas Jefferson University

Philadelphia, Pennsylvania, 19107, United States

Biospecimen

Retention: SAMPLES WITHOUT DNA

Whole blood

MeSH Terms

Conditions

Persistent Fetal Circulation Syndrome

Condition Hierarchy (Ancestors)

Hypertension, PulmonaryLung DiseasesRespiratory Tract DiseasesInfant, Newborn, DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

Euming Chong, MD
Christiana Hospital / Thomas Jefferson University Hospital
PRINCIPAL INVESTIGATOR
Constance Andrejko, DO
Christiana Hospital / Thomas Jefferson University Hospital
PRINCIPAL INVESTIGATOR

Enrollment

10 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

March 2, 2007

First Posted

March 6, 2007

Study Start

February 2007

Date type not reported

This date has not been verified as actual or estimated.

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Phase 4Completed

NCT00005497

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Completed

NCT01203423

Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study

Completed

clinical diagnosis of PPHN

You may not qualify if:

newborns with evidence of structural heart disease, congenital anomalies and prior use of inhaled nitric oxide.

Contact the study team to confirm eligibility.

Primary Completion

September 2008

Actual (reported)

Study Completion

September 2008

Actual (reported)

Last Updated

July 11, 2016

Record last verified: 2009-05

Source record

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Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT00443859
Data provider: ClinicalTrials.gov
Source updated: 2016-07-11
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:34:34 UTC

Locations

US(2)

Study Stopped

N-Terminal Pro-brain Natriuretic Peptide Hormone and Persistent Pulmonary Hypertension

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Study Arms (1)

PPHN

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (2)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Study Arms (1)

PPHN

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (2)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations