NCT00439478

Brief Summary

We aim to assess the incidence of oral and dental adverse events after high-dose radioiodine therapy for differentiated thyroid cancer.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
202

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2004

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2004

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2006

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

February 22, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 23, 2007

Completed
Last Updated

November 14, 2007

Status Verified

October 1, 2007

First QC Date

February 22, 2007

Last Update Submit

November 13, 2007

Conditions

Thyroid Cancer

Keywords

Radioiodine, Thyroid Cancer, Sialadenitis, Xerostomia

Interventions

RadioiodineDRUG

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • histologically confirmed differentiated thyroid cancer
  • status after total thyroidectomy
  • status after subsequent high-dose radioiodine treatment
  • regular follow-up by a board-certified dentist
  • a minimum follow-up of 1 year after radioiodine therapy.

You may not qualify if:

  • anaplastic thyroid cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital

Basel, 4031, Switzerland

Location

MeSH Terms

Conditions

Thyroid NeoplasmsSialadenitisXerostomia

Interventions

Iodine-131

Condition Hierarchy (Ancestors)

Endocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsHead and Neck NeoplasmsEndocrine System DiseasesThyroid DiseasesSalivary Gland DiseasesMouth DiseasesStomatognathic Diseases

Study Officials

  • Beat Müller, MD

    Division of Endocrinology, University Hospital Basel

    STUDY DIRECTOR

Study Design

Study Type
observational
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 22, 2007

First Posted

February 23, 2007

Study Start

September 1, 2004

Study Completion

September 1, 2006

Last Updated

November 14, 2007

Record last verified: 2007-10

Locations

CH(1)