NCT00438373

Brief Summary

The purpose of this study is to evaluate if there is an association between the serum LH receptor expression on the day of hCG administration or the day of oocyte retrieval and the retrieval rates at oocyte pick up

Trial Health

33
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Trial recruitment is currently suspended
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2007

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
suspended

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2007

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 21, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 22, 2007

Completed
8.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2016

Completed
Last Updated

February 26, 2015

Status Verified

February 1, 2015

Enrollment Period

9 years

First QC Date

February 21, 2007

Last Update Submit

February 25, 2015

Conditions

Subfertility

Keywords

Subfertility, Luteinizing hormone, receptor

Outcome Measures

Primary Outcomes (1)

  • LH/hCG receptor expression

    at oocyte retrieval

Eligibility Criteria

Age18 Years - 39 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

infertile patients undergoing assisted reproduction tratment

You may qualify if:

  • Age \<39 years,
  • Body mass index (BMI) between 18 and 29 kg/m2,
  • Presence of both ovaries,
  • FSH levels \<10 IU/l.

You may not qualify if:

  • Endometriomas,
  • Polycystic ovarian syndrome.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Unit of Human Reproduction, 1st Department of Obstetrics & Gynecology, AUTH, Papageorgiou Hospital

Thessaloniki, 56429, Greece

Location

Related Publications (2)

  • Patsoula E, Loutradis D, Drakakis P, Michalas L, Bletsa R, Michalas S. Messenger RNA expression for the follicle-stimulating hormone receptor and luteinizing hormone receptor in human oocytes and preimplantation-stage embryos. Fertil Steril. 2003 May;79(5):1187-93. doi: 10.1016/s0015-0282(03)00071-2.

    PMID: 12738515BACKGROUND

  • Patsoula E, Loutradis D, Drakakis P, Kallianidis K, Bletsa R, Michalas S. Expression of mRNA for the LH and FSH receptors in mouse oocytes and preimplantation embryos. Reproduction. 2001 Mar;121(3):455-61. doi: 10.1530/rep.0.1210455.

    PMID: 11226072BACKGROUND

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Study Officials

  • Basil C Tarlatzis, MD, PhD

    Unit of Human Reproduction, 1st Department of Obs & Gyne, Aristotle University of Thessaloniki, Papageorgiou Hospital, Greece

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 21, 2007

First Posted

February 22, 2007

Study Start

January 1, 2007

Primary Completion

January 1, 2016

Study Completion

January 1, 2016

Last Updated

February 26, 2015

Record last verified: 2015-02

Locations

GR(1)