Comparison Between Fixed- Versus Mobile-bearing TKA
1 other identifier
interventional
160
1 country
1
Brief Summary
The purpose of the study is to analyse the clinical and radiological results of a postero-stabilized TKA by using a mobile bearing versus fixed. Only patients with medial femorotibial arthritis will be included. The consequences on the patellofemoral joint will be thoroughly analysed on skyline view.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Feb 2007
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2007
CompletedFirst Submitted
Initial submission to the registry
February 13, 2007
CompletedFirst Posted
Study publicly available on registry
February 14, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2009
CompletedMay 15, 2026
May 1, 2026
2.4 years
February 13, 2007
May 13, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
International Knee Society Score
2, 6 and 12 monthes after surgery
Secondary Outcomes (3)
Patellofemoral tilt on skyline view, measurement of two angles :
2 and 12 monthes after surgery
patellar tilt
2 and 12 monthes after surgery
patellar displacement from the center of the trochlear groove
2 and 12 monthes after surgery
Study Arms (2)
mobile-bearing TKA
EXPERIMENTALfixed- bearing TKA
ACTIVE COMPARATORInterventions
Eligibility Criteria
You may qualify if:
- Medial medial femorotibial arthritis requiring an arthroplasty
- Age between 50y and 90y
You may not qualify if:
- Lateral femorotibial arthritis
- Inflammatory disease
- Stiff knee with flexion under 90°
- Revision TKA
- Previous surgery (except meniscectomy)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Sebastien Lustig
Lyon, 69300, France
Related Publications (2)
Sappey-Marinier E, Swan J, Maucort-Boulch D, Batailler C, Malatray M, Neyret P, Lustig S, Servien E. No significant clinical and radiological differences between fixed versus mobile bearing total knee replacement using the same semi-constrained implant type: a randomized controlled trial with mean 10 years follow-up. Knee Surg Sports Traumatol Arthrosc. 2022 Feb;30(2):603-611. doi: 10.1007/s00167-020-06346-1. Epub 2020 Nov 5.
PMID: 33151364RESULTSappey-Marinier E, de Abreu FGA, O'Loughlin P, Gaillard R, Neyret P, Lustig S, Servien E. No difference in patellar position between mobile-bearing and fixed-bearing total knee arthroplasty for medial osteoarthritis: a prospective randomized study. Knee Surg Sports Traumatol Arthrosc. 2020 May;28(5):1542-1550. doi: 10.1007/s00167-019-05565-5. Epub 2019 Jun 19.
PMID: 31218390RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Philippe Neyret, MD
Hospices Civils de Lyon
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 13, 2007
First Posted
February 14, 2007
Study Start
February 1, 2007
Primary Completion
July 1, 2009
Study Completion
July 1, 2009
Last Updated
May 15, 2026
Record last verified: 2026-05