NCT00432757

Brief Summary

The purpose of this study is to evaluate the efficacy and safety of an anti-allergy drug with a contact lens compared to placebo in preventing ocular itching associated with allergic conjunctivitis

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P25-P50 for phase_3

Timeline
Completed

Started Jan 2007

Shorter than P25 for phase_3

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2007

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 4, 2007

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 8, 2007

Completed
21 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2007

Completed
Last Updated

April 9, 2009

Status Verified

April 1, 2009

First QC Date

February 4, 2007

Last Update Submit

April 8, 2009

Conditions

Keywords

allergic conjunctivitis, ophthalmology, multicenter, controlled

Outcome Measures

Primary Outcomes (1)

  • Ocular itching

Secondary Outcomes (1)

  • Conjunctival, ciliary, and episcleral redness; chemosis and mucous discharge; tearing and lid swelling

Interventions

Eligibility Criteria

Age8 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • history of ocular allergies and a positive skin test reaction to cat hair, cat dander, grasses, ragweed, and/or trees within the past 24 months; successful soft contact lens wearer who has frequently worn contact lenses for at least one month or more

You may not qualify if:

  • active ocular infection; clinically significant blepharitis; follicular conjunctivitis; pterygium; narrow angle glaucoma; dry eye syndrome; ocular surgery within past 6 months; pregnancy or lactation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Unknown Facility

Los Angeles, California, United States

Location

Unknown Facility

Charlotte, North Carolina, United States

Location

Unknown Facility

Memphis, Tennessee, United States

Location

MeSH Terms

Conditions

Conjunctivitis, Allergic

Interventions

Ketotifen

Condition Hierarchy (Ancestors)

ConjunctivitisConjunctival DiseasesEye DiseasesHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Intervention Hierarchy (Ancestors)

ThiophenesSulfur CompoundsOrganic ChemicalsPiperidinesHeterocyclic Compounds, 1-RingHeterocyclic Compounds

Study Officials

  • Brian Pall, OD, MS, FAAO

    Vistakon Pharmaceuticals

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
DOUBLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

February 4, 2007

First Posted

February 8, 2007

Study Start

January 1, 2007

Study Completion

March 1, 2007

Last Updated

April 9, 2009

Record last verified: 2009-04

Locations