NCT00429819|Completed
Loading search results
Sponsor study identifier
Secondary identifiers
OTHER_GRANT · 3200B0-113685
observational
100
1 country
1
Study Start
December 2006
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
June 2014
Actual (reported)Study Completion
December 2014
Actual (reported)We hypothesize that glaucoma patients demonstrate an impaired retinal vascular response to the flicker stimulus, and that this disturbance is predictive of the progression of glaucomatous damage. The response of a major temporal superior and inferior retinal artery and vein to a 60 seconds 12.5 Hz flicker light stimulation in 50 glaucoma patients, 50 ocular hypertensives and 50 controls (using the Retinal Vessel Analyzer) and to investigate how intraocular pressure relates to neurovascular coupling. In addition, 50 glaucoma patients and 50 ocular hypertension patients will be followed for 3 years for functional (visual field, automated perimetry with Octopus device) and morphological (retinal nerve fiber layer thickness, Optical Coherence Tomography Stratus (OCT) device) glaucomatous damage progression, in order to test the predictive power of the retinal vascular flicker response for glaucoma progression.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2014
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
December 2006
Date type not reportedThis date has not been verified as actual or estimated.
January 31, 2007
Actual (reported)February 1, 2007
Actual (reported)June 2014
Actual (reported)December 2014
Actual (reported)Prognostic value of Flicker Response in glaucoma patients and ocular hypertension (OHT)
up to 3 years
glaucoma patients ocular hypertension
University Eye Clinic
Basel, Canton of Basel-City, 4031, Switzerland
Selim Orgül, MD
University Eye Clinic Basel
100 participants (actual enrollment reported by the registry).
First Submitted
January 31, 2007
First Posted
February 1, 2007
Study Start
December 2006
Date type not reportedThis date has not been verified as actual or estimated.
Tolerability, Safety and Efficacy of RKI983 Eye Drops in Subjects With Primary Open Angle Glaucoma and Ocular Hypertension
Contact the study team to confirm eligibility.
Primary Completion
June 2014
Actual (reported)Study Completion
December 2014
Actual (reported)Last Updated
December 16, 2014
Record last verified: 2014-12
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: