NCT00429767|CompletedDMC
Sustained Release d-Amphetamine & Buprenorphine on Drug Seeking Behavior in Opioid & Cocaine Dependent Individuals
Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine: Study 1
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Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine: Study 1
Sponsor study identifier
Secondary identifiers
NIH
OTHER · NIDA
observational
16
1 country
1
Study Start
January 2007
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
January 2010
Actual (reported)Study Completion
January 2010
Actual (reported)The purpose of this study is to determine whether maintenance on different oral doses of sustained release d-amphetamine (SR-AMP) combined with constant-dose sublingual buprenorphine (BUP) is safe and well tolerated and decreases self-administration of cocaine alone or combined with hydromorphone (HYD). Secondary aims are to determine whether SR-AMP attenuates the subjective and physiological effects of cocaine during drug sampling periods prior to choice opportunities.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 2010
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 2007
Date type not reportedThis date has not been verified as actual or estimated.
January 30, 2007
Actual (reported)February 1, 2007
Actual (reported)January 2010
Actual (reported)January 2010
Actual (reported)Heroin dependent and Cocaine abuse or dependent research volunteers.
Wayne State University
Detroit, Michigan, 48207, United States
Stoltman JJ, Woodcock EA, Lister JJ, Greenwald MK, Lundahl LH. Exploration of the telescoping effect among not-in-treatment, intensive heroin-using research volunteers. Drug Alcohol Depend. 2015 Mar 1;148:217-20. doi: 10.1016/j.drugalcdep.2015.01.010. Epub 2015 Jan 19.
Greenwald MK, Lundahl LH, Steinmiller CL. Sustained release d-amphetamine reduces cocaine but not 'speedball'-seeking in buprenorphine-maintained volunteers: a test of dual-agonist pharmacotherapy for cocaine/heroin polydrug abusers. Neuropsychopharmacology. 2010 Dec;35(13):2624-37. doi: 10.1038/npp.2010.175. Epub 2010 Sep 29.
Mark Greenwald, PhD
Wayne State University
First Submitted
January 30, 2007
First Posted
February 1, 2007
Study Start
January 2007
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
January 2010
Buprenorphine Maintenance Treatment of Opioid Dependence in Primary Care: A Randomized Clinical Trial
Contact the study team to confirm eligibility.
Study Completion
January 2010
Actual (reported)Last Updated
June 5, 2012
Record last verified: 2012-06
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Source: ClinicalTrials.gov.
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