NCT00428740

Brief Summary

Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for patients with coexisting glaucoma and visually significant cataracts.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2005

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2005

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2005

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

January 29, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 30, 2007

Completed
Last Updated

January 30, 2007

Status Verified

January 1, 2007

First QC Date

January 29, 2007

Last Update Submit

January 29, 2007

Conditions

GlaucomaFiltering SurgeryIntraocular Pressure

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Underwent triple procedure
  • At leas 3 years of follow-up after surgery
  • IOP \<18mmHg at each postoperative visit
  • A minimum of 5 visual field examinations
  • A reference visual field defect score of 16 or less
  • Good reliability indices of visual field

You may not qualify if:

  • Any other significant ocular diseases or intraocular surgical histories,
  • Diseases that may affect visual field or diabetes

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yonsei University College of Medicine

Seoul, 135-720, South Korea

Location

Related Publications (1)

  • Hong S, Seong GJ, Hong YJ. Long-term intraocular pressure fluctuation and progressive visual field deterioration in patients with glaucoma and low intraocular pressures after a triple procedure. Arch Ophthalmol. 2007 Aug;125(8):1010-3. doi: 10.1001/archopht.125.8.1010.

    PMID: 17698746DERIVED

MeSH Terms

Conditions

Glaucoma

Condition Hierarchy (Ancestors)

Ocular HypertensionEye Diseases

Study Officials

  • Gong Je Seong, MD, PhD

    Yondgong Severance Hospital, Yonsei University College of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
DEFINED POPULATION
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 29, 2007

First Posted

January 30, 2007

Study Start

October 1, 2005

Study Completion

December 1, 2005

Last Updated

January 30, 2007

Record last verified: 2007-01

Locations

KR(1)