The Influence of Hip Strengthening Exercises on Walking Patterns and Muscle Strength in Persons With Knee Osteoarthritis

NCT00427843 | Completed DMC

• 1 other identifier: REH-324-06
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine the influence of a home program of exercises for the hip muscles which support the pelvis on walking patterns and hip muscle strength in people with knee osteoarthritis. Following a hip muscle strengthening program, we hypothesize that participants with knee osteoarthritis will demonstrate decreased loading at the knee joint during walking and greater strength of the hip muscles.

Conditions

Osteoarthritis, Knee

Keywords

osteoarthritis; knee; gait; muscle strength; hip; exercise

Outcome Measures

Primary Outcomes (2)

• Walking variables: hip and knee abductor and adductor moments

  baseline and after 8 weeks

• Muscle strength measures: isometric and isokinetic peak torque measures for the hip abductor and adductor muscles

  baseline and after 8 weeks

Secondary Outcomes (4)

• Radiographs: lower limb frontal plane alignment measures - limb alignment in degrees; grading of knee osteoarthritis severity (total score out of 13)

  baseline

• Speed of performance on the Five-Times-Sit-to-Stand Test

  baseline and after 8 weeks

• Total score on the WOMAC pain subscale and the WOMAC physical function subscale

  baseline and after 8 weeks

• Total score obtained for the physical activity scale (PASE)

  baseline and after 8 weeks

Study Arms (1)

Exercise Home-Based Program

EXPERIMENTAL

Patients with knee OA will be taught a home-based exercise program for the hip abductor muscles during the initial visit. The exercise program will be performed 3 times per week for 8 weeks.

Behavioral: home exercise program for the hip abductor muscles

Interventions

home exercise program for the hip abductor muscles BEHAVIORAL

All patients with knee OA will be taught a home-based exercise program for the hip abductor muscles during the initial visit. Patients will be instructed in the following program: contraction of the gluteus medius muscle during functional activities (gait, stepping sideways up on a step and standing on one leg); and side lying isotonic hip abduction exercises using graded resistance elastic bands positioned around the distal thighs. The program will be performed 3 times per week for 8 weeks and subjects will record exercise frequency and level of resistance on exercise calendars. Follow-up visits will occur at the end of week 1 and week 4 for review and progression of exercises. A telephone follow-up call will occur for support and participants will be encouraged to call with any questions or concerns.

Exercise Home-Based Program

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• age greater than or equal to 40 years
• self-reported pain in the knee(s) for most days of the month
• at least some difficulty in daily function due to knee osteoarthritis
• radiographic evidence of knee osteoarthritis or documented evidence of cartilage loss in the knee by arthroscopy surgery or magnetic resonance imaging.

You may not qualify if:

• corticosteroid injection into either knee within the previous three months
• other significant medical problems (including significant heart disease, stroke and active treatment for cancer) that would prevent participants from being able to perform a hip exercise program or to participate in tests of walking performance and hip muscle strength
• known osteoarthritis or previous trauma affecting one or both hips
• previous replacement of any joint in the lower extremities.
• receiving rehabilitation services for knee osteoarthritis or performing a hip strengthening program at the time of testing
• participants who have had a dual-energy x-ray absorptiometry (DEXA) for bone density analysis or more than one x-ray of the chest, abdomen or hip in the past 6 months

Sponsors & Collaborators

• Queen's University: lead

Study Sites (1)

School of Rehabilitation Therapy, Queen's University

Kingston, Ontario, K7L 3N6, Canada

Location

Related Publications (1)

• Sled EA, Khoja L, Deluzio KJ, Olney SJ, Culham EG. Effect of a home program of hip abductor exercises on knee joint loading, strength, function, and pain in people with knee osteoarthritis: a clinical trial. Phys Ther. 2010 Jun;90(6):895-904. doi: 10.2522/ptj.20090294. Epub 2010 Apr 8.

  PMID: 20378679 DERIVED

MeSH Terms

Conditions

Osteoarthritis, Knee; Osteoarthritis; Motor Activity

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Behavior

Study Officials

• Elsie G. Culham, PhD

  Queen's University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: January 25, 2007
• First Posted: January 29, 2007
• Study Start: January 1, 2007
• Primary Completion: May 1, 2008
• Study Completion: September 1, 2008
• Last Updated: October 15, 2008

Record last verified: 2008-10

Locations

CA (1)