GlObal Secondary Prevention strategiEs to Limit Event Recurrence After Myocardial Infarction. GOSPEL Study
1 other identifier
interventional
3,200
2 countries
74
Brief Summary
Cardiac rehabilitation programmes are a proven treatment for individuals with recent myocardial infarction, resulting in reduced morbidity and mortality compared to usual care. Unfortunately, following completion of a cardiac rehabilitation programme, risk factors and lifestyle behaviours may deteriorate. The GOSPEL study investigates the benefits of a programme of continued educational and behavioural intervention to achieve optimal long-term secondary prevention goals.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Dec 2000
Longer than P75 for not_applicable
74 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2000
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2005
CompletedFirst Submitted
Initial submission to the registry
January 12, 2007
CompletedFirst Posted
Study publicly available on registry
January 15, 2007
CompletedFebruary 3, 2021
January 1, 2007
January 12, 2007
February 2, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (6)
cardiovascular mortality
non fatal re-MI
angina requiring hospitalization
urgent revascularization procedures
hospitalization for heart failure
non fatal stroke
Interventions
Eligibility Criteria
You may qualify if:
- Recent myocardial infarction (within 3 months after the index event)
- Standard rehabilitation program of 3-6 weeks performed
- Informed consent (obtained before any study specific procedure)
You may not qualify if:
- Age \> 75 years
- Any condition that in the opinion of the investigator would jeopardize the evaluation of efficacy or be associated with poor adherence to the protocol;
- Presence of any non-cardiac disease (e.g. cancer) that is likely to significantly shorten life expectancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (74)
Ospedale San Donato
Arezzo, AR, Italy
Az Osp Giuseppe Moscati
Avellino, AV, Italy
Fondazione Salvatore Maugeri
Cassano delle Murge, BA, Italy
Ospedale Romano di Lombardia
Romano Lombardo, BG, Italy
Fondazione Salvatore Maugeri
Telese Terme, BN, Italy
Ospedale Bellaria
Bologna, BO, Italy
Presidio Gazzaniga
Gazzaniga, BS, Italy
Fondazione Salvatore Maugeri
Gussago, BS, Italy
Azienda Ospedaliera S Anna e S Sebastiano
Caserta, CE, Italy
Casa di Cura Villa Pini d'Abruzzo
Chieti, CH, Italy
Ospedale Umberto I
Bellano, Como, Italy
Ospedale Santa Marta
Rivolta d'Adda, CR, Italy
Ospedale Civile Minervini
Mormanno, CS, Italy
Ospedale Civile C Chidichino
Trebisacce, CS, Italy
Ospedale Ascoli Tomaselli
Catania, CT, Italy
Ospedale Cannizzarro
Catania, CT, Italy
Azienda Ospedaliera Mater Domini
Catanzaro, CZ, Italy
Az Ospedaliera-Universitaria Careggi
Florence, FI, Italy
Ospedale La Colletta
Arenzano, GE, Italy
Polo Ospedaliero Rapallo S Margherita
Rapallo, GE, Italy
ospedale Generale Provinciale
Gorizia, GO, Italy
Ospedale San Leopoldo
Merate, Lecco, Italy
Presidio Ospedaliero F Ferrari
Casarano, LE, Italy
Ospedale Civile Bassa Val di Cecina
Cecina, LI, Italy
Ospedale Civile Campo di marte
Lucca, LU, Italy
Presidio di Riabilitazione Multifunzionale
Bozzolo, MI, Italy
Casa di Cura Ambrosiana
Cesano Boscone, MI, Italy
Ospedale San Gerardo
Monza, MI, Italy
Presidio Ospedaliero di Passirana
Passirana - Rho, MI, Italy
Fondazione Salvatore Maugeri
Tradate, MI, Italy
Fondazione Salvatore Maugeri
Veruno, Novara, Italy
Ospedale Buccheri la Ferla Fatebenefratelli
Palermo, PA, Italy
Casa di Cura San Giacomo
Ponte dell'Olio, PC, Italy
Ospedale di Camposanpiero
Camposanpiero, PD, Italy
Predisio Ospedaliero Città di Castello
Città di Castello, PG, Italy
Nuovo Ospedale S Giovanni Battista
Foligno, PG, Italy
Ospedale Calai
Gualdo Tadino, PG, Italy
Azienda Ospedaliera di Perugia
Perugia, PG, Italy
Ex Ospedale Grocco
Perugia, PG, Italy
ospedale della Val di Nievole
Pescia, Point, Italy
Ospedale Civile
Sacile, Pordenone, Italy
Fondazione Salvatore Maugeri
Montescano, PV, Italy
Azienda Ospedaliera San Carlo
Potenza, PZ, Italy
Casa di Cura Villa Maria Cecilia
Cotignola, RA, Italy
Ospedale Infermi
Rimini, RA, Italy
Policlinico Madonna della Consolazione
Reggio Calabria, RC, Italy
Ospedale Sant'Anna
Castelnovo ne' Monti, RE, Italy
Ospedale Civile San Sebastiano
Correggio, RE, Italy
Ospedale E Morelli
Sondalo, SO, Italy
Ospedale SS Annunziata
Taranto, TA, Italy
Ospedale di ALA
Ala, TN, Italy
Ospedale Provinciale S Pancrazio
Arco, TN, Italy
Presidio Ospedaliero
Montebelluna, TV, Italy
Ospedale Civile
Mirano, VE, Italy
Ospedale Civile
San Donà di Piave, VE, Italy
Ospedale Beauregard
Aosta, Italy
Ospedali Riuniti
Bergamo, Italy
Casa di Cura Villa Aprica
Como, Italy
Casa di Cura Pineta del Carso
Duino-Aurisina, Italy
Presidio Ospedalier S Giovanni
Mezzolombardo, Italy
Fondazione Don Gnocchi
Milan, Italy
Istituti Clinici Perfezionamento
Milan, Italy
Ospedale S Luca-Centro Auxologico
Milan, Italy
Pio Albergo Trivulzio
Milan, Italy
Azienda Ospedaliera Vincenzo Monaldi
Napoli, Italy
Policlinico Universitario Federico II
Napoli, Italy
Fondazione Salvatore maugeri
Pavia, Italy
Ospedale Forlanini
Roma, Italy
Ospedale Santo Spirito
Roma, Italy
Villa Betania
Roma, Italy
Ospedale Evangelico Valdese
Torino, Italy
Ospedale Mauriziano
Torino, Italy
ospedale Civile S Bortolo
Vicenza, Italy
Cardiocentro Ticino
Lugano, Switzerland
Related Publications (2)
Giannuzzi P, Temporelli PL, Maggioni AP, Ceci V, Chieffo C, Gattone M, Griffo R, Marchioli R, Schweiger C, Tavazzi L, Urbinati S, Valagussa F; GOSPEL. GlObal Secondary Prevention strategiEs to Limit event recurrence after myocardial infarction: the GOSPEL study. A trial from the Italian Cardiac Rehabilitation Network: rationale and design. Eur J Cardiovasc Prev Rehabil. 2005 Dec;12(6):555-61. doi: 10.1097/01.hjr.0000186623.60486.26.
PMID: 16319545BACKGROUNDGiannuzzi P, Temporelli PL, Marchioli R, Maggioni AP, Balestroni G, Ceci V, Chieffo C, Gattone M, Griffo R, Schweiger C, Tavazzi L, Urbinati S, Valagussa F, Vanuzzo D; GOSPEL Investigators. Global secondary prevention strategies to limit event recurrence after myocardial infarction: results of the GOSPEL study, a multicenter, randomized controlled trial from the Italian Cardiac Rehabilitation Network. Arch Intern Med. 2008 Nov 10;168(20):2194-204. doi: 10.1001/archinte.168.20.2194.
PMID: 19001195RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Pantaleo Giannuzzi, MD
Fondazione Maugeri - Veruno (NO)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
January 12, 2007
First Posted
January 15, 2007
Study Start
December 1, 2000
Study Completion
December 1, 2005
Last Updated
February 3, 2021
Record last verified: 2007-01