A Proof of Biological Efficacy Study Assessing the Potential of Piboserod, a Specific 5-HT4 Antagonist, for the Treatment of Symptomatic Congestive Heart Failure on Top of Usual Evidence Based Pharmacological Treatment
Sponsor study identifier
interventional
137
3 countries
17
Study Start
January 2006
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
July 2007
Actual (reported)The purpose of this study is to determine whether piboserod, a serotonin-4 receptor antagonist, is effective for the treatment of patients with congestive heart failure.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 2007
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 2006
Date type not reportedThis date has not been verified as actual or estimated.
January 11, 2007
Actual (reported)January 12, 2007
Actual (reported)July 2007
Actual (reported)Change from baseline to end-of-therapy in Left Ventricular Ejection Fraction, as measured using CMR imaging
6 months
Change in LV systolic and diastolic volume (and/or diameter) by CMR
6 months
Change in NYHA functional class
6 months
Change in various biomarkers for heart failure
6 months
Change in QoL-scores
6 months
Change in 6-minute walk distance
6 months
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Rigshospitalet
Copenhagen, 2100, Denmark
Amager Hospital
Copenhagen, 2300, Denmark
Bispebjerg Hospital
Copenhagen, 2400, Denmark
Frederiksberg Hospital
Frederiksberg, 2000, Denmark
Amtsygehuset i Herlev
Herlev, 2730, Denmark
Hvidovre Hospital
Hvidovre, 2650, Denmark
Odense Universitets Hospital
Odense, 5000, Denmark
Kjekshus JK, Torp-Pedersen C, Gullestad L, Kober L, Edvardsen T, Olsen IC, Sjaastad I, Qvigstad E, Skomedal T, Osnes JB, Levy FO. Effect of piboserod, a 5-HT4 serotonin receptor antagonist, on left ventricular function in patients with symptomatic heart failure. Eur J Heart Fail. 2009 Aug;11(8):771-8. doi: 10.1093/eurjhf/hfp087. Epub 2009 Jun 30.
Christian Torp-Pedersen, Dr. Med
Bispebjerg Hospital
137 participants (actual enrollment reported by the registry).
First Submitted
January 11, 2007
First Posted
January 12, 2007
Study Start
January 2006
Date type not reportedThis date has not been verified as actual or estimated.
Study of DITPA in Patients With Congestive Heart Failure
Contact the study team to confirm eligibility.
Svendborg Sygehus
Svendborg, 5700, Denmark
Østlandske Hjertesenter
Moss, 1530, Norway
Fana Hjertesenter
Nesttun, 5221, Norway
Rikshospitalet
Oslo, 0027, Norway
Ullevål Universitetssykehus
Oslo, 0407, Norway
Stavanger Universitetssjukehus
Stavanger, Norway
St. Olavs Hospital
Trondheim, 7006, Norway
Castel Hill Hospital
Cottingham, East Yorkshire, HU16 5JQ, United Kingdom
Bridlington and District General Hospital
Bridlington, YO16 4QP, United Kingdom
Western Infirmary
Glasgow, G11 6NT, United Kingdom
Study Completion
July 2007
Actual (reported)Last Updated
August 3, 2007
Record last verified: 2007-08
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: