NCT00415792

Brief Summary

hCG and GnRH agonist can be used to induce final oocyte maturation and ovulation in IVF cycles. These two approaches will be compared in this study in terms of pregnancy rates and embryological data using patients with hyper-response to IVF drugs.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Nov 2003

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2003

Completed
1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2005

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

December 22, 2006

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 25, 2006

Completed
Last Updated

January 5, 2007

Status Verified

January 1, 2007

First QC Date

December 22, 2006

Last Update Submit

January 4, 2007

Conditions

Infertility

Keywords

Ovulation inductionhCGGnRH agonisthyper-responders

Outcome Measures

Primary Outcomes (1)

  • Ongoing pregnancy per embryo transfer

Secondary Outcomes (3)

  • Biochemical pregnancy per embryo transfer

  • Clinical pregnancy per embryo transfer

  • Embryological data

Interventions

Arvekap, PregnylDRUG

Eligibility Criteria

Age18 Years - 50 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Hyper-responder patients (\>20 oocytes retrieved)

You may not qualify if:

  • Normal responders
  • Poor responders
  • PCOS

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Eugonia

Athens, 11528, Greece

Location

Related Publications (1)

  • Griesinger G, Diedrich K, Devroey P, Kolibianakis EM. GnRH agonist for triggering final oocyte maturation in the GnRH antagonist ovarian hyperstimulation protocol: a systematic review and meta-analysis. Hum Reprod Update. 2006 Mar-Apr;12(2):159-68. doi: 10.1093/humupd/dmi045. Epub 2005 Oct 27.

    PMID: 16254001BACKGROUND

MeSH Terms

Conditions

Infertility

Interventions

Chorionic Gonadotropin

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Intervention Hierarchy (Ancestors)

GonadotropinsPeptide HormonesHormonesHormones, Hormone Substitutes, and Hormone AntagonistsPlacental HormonesPeptidesAmino Acids, Peptides, and ProteinsPregnancy ProteinsProteins

Study Officials

  • Tryfon Lainas, PhD

    Eugonia

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 22, 2006

First Posted

December 25, 2006

Study Start

November 1, 2003

Study Completion

July 1, 2005

Last Updated

January 5, 2007

Record last verified: 2007-01

Locations

GR(1)