NCT00414401

Brief Summary

Although beta-blockers are known to prolong survival for patients with reduced left ventricular ejection fraction, their use in the community and the VA is suboptimal.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,500

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2001

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2001

Completed
5.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2006

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

December 19, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 21, 2006

Completed
Last Updated

April 7, 2015

Status Verified

December 1, 2006

First QC Date

December 19, 2006

Last Update Submit

April 6, 2015

Conditions

Heart Failure, Congestive

Outcome Measures

Primary Outcomes (1)

  • Prescription for any beta-blocker

Secondary Outcomes (1)

  • Prescription for carvedilol or metoprolol succinate

Study Arms (1)

Arm 1

OTHER
Behavioral: Clinical Reminder

Interventions

Clinical ReminderBEHAVIORAL
Arm 1

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Those undergoing echocardiography at one of the participating laboratories with an ejection fraction \< 45%.

You may not qualify if:

  • aortic stenosis, mitral stenosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA Palo Alto Health Care System, Palo Alto, CA

Palo Alto, California, 94304-1290, United States

Location

Related Publications (2)

  • Heidenreich PA, Gholami P, Sahay A, Massie B, Goldstein MK. Clinical reminders attached to echocardiography reports of patients with reduced left ventricular ejection fraction increase use of beta-blockers: a randomized trial. Circulation. 2007 Jun 5;115(22):2829-34. doi: 10.1161/CIRCULATIONAHA.106.684753. Epub 2007 May 21.

    PMID: 17515459RESULT

  • Heidenreich PA, Chacko M, Goldstein MK, Atwood JE. ACE inhibitor reminders attached to echocardiography reports of patients with reduced left ventricular ejection fraction. Am J Med. 2005 Sep;118(9):1034-7. doi: 10.1016/j.amjmed.2004.12.028. No abstract available.

    PMID: 16164891RESULT

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Paul A. Heidenreich, MD MS

    VA Palo Alto Health Care System, Palo Alto, CA

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 19, 2006

First Posted

December 21, 2006

Study Start

May 1, 2001

Study Completion

June 1, 2006

Last Updated

April 7, 2015

Record last verified: 2006-12

Locations

US(1)