NCT00407238

Completed

Corneal Barrier Function With Multi-Purpose Solutions

Southern California College of Optometry at Marshall B. Ketchum University Source

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Other study identifiers

Sponsor study identifier

6-08

Study Type

interventional

Estimated enrollment

25

Locations

1 country

Sites

1

Timeline

Study Start

November 2006

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

Not reported

Date not reported

Study Completion

March 2007

Actual (reported)

Brief Summary

The purpose of this study is to evaluate the effect on epithelial barrier function of three emarketed multi-purpose solution applied to the human eye with hydrogel lenses as during normal regimen use.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Estimated enrollment: 25 participants
Study completion date: March 2007
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

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Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
November 2006
Date type not reported
This date has not been verified as actual or estimated.
First Submitted
November 17, 2006
Actual (reported)
First Posted
December 4, 2006
Actual (reported)
Study Completion
March 2007
Actual (reported)

Last Updated: October 23, 2007
Status Verified: October 2007
Last Update Submitted: October 21, 2007

Conditions

Contact Lens Care

Keywords

barrier function, multi-purpose solutions, silicone hydrogel contact lenses

Outcome Measures

Primary Outcomes (1)

Ratio of fluorescein dye penetration rate of test eye vs. control

Secondary Outcomes (1)

Corneal fluorescein staining

Interventions

Multi-purpose solutions (polyquaternium-1 and PHMB)Device

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Adapted daily soft contact lens wearers, at least 18 years of age, vision correctable to 20/40

You may not qualify if:

Sponsors & Collaborators

Alcon Research
Industrycollaborator
Southern California College of Optometry at Marshall B. Ketchum University
Otherlead

Study Sites (1)

Southern California College of Optometry

Fullerton, California, 92831, United States

Study Officials

Jerry R Paugh, OD, PhD
Southern California College of Optometry at Marshall B. Ketchum University
PRINCIPAL INVESTIGATOR

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: DOUBLE
Purpose: TREATMENT
Intervention Model: CROSSOVER
Sponsor Type: OTHER

Study Record Dates

First Submitted

November 17, 2006

First Posted

December 4, 2006

Study Start

November 2006

Date type not reported

This date has not been verified as actual or estimated.

Study Completion

March 2007

Actual (reported)

NCT00884806

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Not ApplicableCompleted

NCT00885092

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Not ApplicableCompleted

NCT06592521

OPTI-FREE Family STUDY

Not ApplicableWithdrawn

NCT06588400

AOSEPT (CLEAR CARE) PLUS Study

Not ApplicableWithdrawn

NCT01494818

Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues

Not ApplicableCompleted

Ocular or systemic allergies, abnormalities of the cornea, active ocular infection, prior keratorefractive surgery, use of ocular medications

Contact the study team to confirm eligibility.

Last Updated

October 23, 2007

Record last verified: 2007-10

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT00407238
Data provider: ClinicalTrials.gov
Source updated: 2007-10-23
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:27:57 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Study Officials

Study Design

Study Record Dates

Source record

Locations