NCT00404872

Brief Summary

Cardiovascular disease (CVD) affects millions of people in the United States; each year, more people die from CVD than from any other disease. Individuals with low levels of n-3 fatty acids and high levels of trans-fatty acids may have an increased risk of developing CVD. This study will evaluate the link between fatty acids and the presence of CVD in older adults.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,766

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 1989

Longer than P75 for all trials

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1989

Completed
17.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2006

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2006

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

November 27, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 29, 2006

Completed
Last Updated

April 14, 2014

Status Verified

April 1, 2014

Enrollment Period

17.4 years

First QC Date

November 27, 2006

Last Update Submit

April 10, 2014

Conditions

Cardiovascular DiseasesHeart Failure, CongestiveAtrial FibrillationCerebrovascular Accident

Keywords

Stroke

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • Participated in the Cardiovascular Health Study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Channing Laboratory, Harvard Medical School

Boston, Massachusetts, 02115, United States

Location

Harvard School of Public Health

Boston, Massachusetts, 02115, United States

Location

Cardiovascular Health Research Unit, University of Washington

Seattle, Washington, 98101, United States

Location

Fred Hutchinson Cancer Research Center

Seattle, Washington, 98101, United States

Location

Related Publications (2)

  • Fried LP, Borhani NO, Enright P, Furberg CD, Gardin JM, Kronmal RA, Kuller LH, Manolio TA, Mittelmark MB, Newman A, et al. The Cardiovascular Health Study: design and rationale. Ann Epidemiol. 1991 Feb;1(3):263-76. doi: 10.1016/1047-2797(91)90005-w.

    PMID: 1669507BACKGROUND

  • Tell GS, Fried LP, Hermanson B, Manolio TA, Newman AB, Borhani NO. Recruitment of adults 65 years and older as participants in the Cardiovascular Health Study. Ann Epidemiol. 1993 Jul;3(4):358-66. doi: 10.1016/1047-2797(93)90062-9.

    PMID: 8275211BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesHeart FailureAtrial FibrillationStroke

Condition Hierarchy (Ancestors)

Heart DiseasesArrhythmias, CardiacPathologic ProcessesPathological Conditions, Signs and SymptomsCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular Diseases

Study Officials

  • Dariush Mozaffarian, MD, DrPH

    Harvard Medical School and Harvard School of Public Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

November 27, 2006

First Posted

November 29, 2006

Study Start

January 1, 1989

Primary Completion

June 1, 2006

Study Completion

June 1, 2006

Last Updated

April 14, 2014

Record last verified: 2014-04

Locations

US(4)