NCT00404482

Brief Summary

Juvenile idiopathic arthritis (JIA) is often associated with chronic anterior uveitis. Presence of vision threatening complications may indicate immunosuppressive therapy. In this study, the experience with cyclosporine A (CsA) as mono- or combination-therapy is analyzed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 1991

Longer than P75 for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1991

Completed
15.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2006

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

November 27, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 28, 2006

Completed
Last Updated

June 3, 2009

Status Verified

June 1, 2009

First QC Date

November 27, 2006

Last Update Submit

June 2, 2009

Conditions

UveitisJuvenile Idiopathic Arthritis

Keywords

uveitisjiaCyclosporine AMTX

Interventions

Cyclosporine ADRUG

Eligibility Criteria

AgeUp to 16 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

patients with JIA and cyclosporin A therapy

You may qualify if:

  • uveitis
  • JIA

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Deutsches Zentrum für Kinder- und Jugendrheumatologie

Garmisch-Partenkirchen, Germany

Location

Department of Ophthalmology at St.-FranziskusHospital

Münster, Germany

Location

Kinder und Jugendrheumatologie St. Josef Stift

Sendenhorst, Germany

Location

MeSH Terms

Conditions

UveitisArthritis, Juvenile

Interventions

Cyclosporine

Condition Hierarchy (Ancestors)

Uveal DiseasesEye DiseasesArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Intervention Hierarchy (Ancestors)

CyclosporinsPeptides, CyclicMacrocyclic CompoundsPolycyclic CompoundsPeptidesAmino Acids, Peptides, and Proteins

Study Officials

  • Christoph Tappeiner, MD

    Department of Ophthalmology at University Bern - Inselspital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

November 27, 2006

First Posted

November 28, 2006

Study Start

January 1, 1991

Study Completion

August 1, 2006

Last Updated

June 3, 2009

Record last verified: 2009-06

Locations

DE(3)