NCT00389558

Brief Summary

The purposes of the study are:

  1. 1.To compare the local efficacy (skin colonization) of 2 commercialized antiseptics used for the disinfection of the dressing application for an epicutaneocavous catheter (EPI).
  2. 2.To evaluate whether the bacteria responsible for nosocomial infection is comparable to the flora diagnosed at the EPI site.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
453

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started Sep 2006

Typical duration for phase_4

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2006

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

October 17, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 19, 2006

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2008

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2008

Completed
Last Updated

September 21, 2009

Status Verified

September 1, 2009

Enrollment Period

2 years

First QC Date

October 17, 2006

Last Update Submit

September 18, 2009

Conditions

Keywords

Skin colonizationAntisepticEpicutaneocavous catheter dressingInfant

Outcome Measures

Primary Outcomes (1)

  • Efficacy on skin colonization of two commercially available antiseptics

    2 weeks

Secondary Outcomes (1)

  • In case of nosocomial infection, relationship with skin bacteria

    2 weeks

Study Arms (2)

2

ACTIVE COMPARATOR

Biseptine

Procedure: disinfection efficacy using Biseptine

1

ACTIVE COMPARATOR

Amukin

Procedure: disinfection efficacy using Amukin

Interventions

Detersion and antiseptic application when changing catheter dressing

Also known as: Biseptine
2

Detersion and antiseptic application when changing catheter dressing

Also known as: Amukin
1

Eligibility Criteria

AgeUp to 3 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • All infants admitted to the Neonatal Intensive Care Unit
  • Epicutaneocavous catheter insertion indication

You may not qualify if:

  • Epicutaneocavous catheter not inserted within the Unit

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Maternite Regionale Universitaire

Nancy, 54042, France

Location

Related Publications (1)

  • Mahieu LM, De Dooy JJ, De Muynck AO, Van Melckebeke G, Ieven MM, Van Reempts PJ. Microbiology and risk factors for catheter exit-site and -hub colonization in neonatal intensive care unit patients. Infect Control Hosp Epidemiol. 2001 Jun;22(6):357-62. doi: 10.1086/501913.

    PMID: 11519913BACKGROUND

MeSH Terms

Conditions

Bacterial Infections

Interventions

Amikacin

Condition Hierarchy (Ancestors)

Bacterial Infections and MycosesInfections

Intervention Hierarchy (Ancestors)

KanamycinAminoglycosidesGlycosidesCarbohydrates

Study Officials

  • Jean-Michel HASCOET, MD

    University of NANCY, France

    STUDY DIRECTOR
  • Monique LUX, Pharmacist

    Maternite Regionale Universitaire

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

October 17, 2006

First Posted

October 19, 2006

Study Start

September 1, 2006

Primary Completion

September 1, 2008

Study Completion

October 1, 2008

Last Updated

September 21, 2009

Record last verified: 2009-09

Locations