NCT00388765

Brief Summary

This study is designed to collect lung washing samples and small pieces of tissue (biopsies) from the lungs of people who do not have any allergies or asthma. These samples will be used by researchers in the future as control samples to compare to samples from people with chronic lung diseases such as allergic asthma or emphysema. Control samples are samples are very important in laboratory experiments so that the researchers can tell what may be labeled as different or abnormal in samples from people with lung disease.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2006

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2006

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

October 13, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 17, 2006

Completed
15 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2006

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2006

Completed
Last Updated

October 5, 2015

Status Verified

October 1, 2008

Enrollment Period

2 months

First QC Date

October 13, 2006

Last Update Submit

October 1, 2015

Conditions

Healthy

Keywords

bronchoscopysample bankresearch study volunteer

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • A subject is eligible for participation in the study if all of the following criteria apply:
  • Ability to give a valid informed consent to participate by signing and dating a written consent form.
  • Male or female with no chronic or acute health concerns that might affect subject safety during the study or interfere with the study results, 18-45 years of age
  • An FEV1 \> 80% of predicted with an FEV1/FVC ratio above 0.70
  • Methacholine PC20 \>16 mg/ml
  • Skin test negative to panel of 12 common aeroallergens

You may not qualify if:

  • A subject is not eligible to participate in this study if any of the following criteria apply:
  • Medications other than for contraception or OTC pain medications to be approved by PI
  • Recent smoker (within 5 years) or has a smoking history exceeding 5 pack years
  • Currently participating in another clinical trial or has participated in an investigational drug trial with in one month of the screening visit
  • Unable, in the judgment of the investigator, to comply with directions and/or tolerate the procedures required for participation in this trial,
  • Pregnant or breast-feeding or has a planned pregnancy during the course of the study
  • History of bleeding with trauma or abnormal clotting tests
  • History of allergy to any of the medications/sedatives that may be administered during the bronchoscopy procedure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Wisconsin

Madison, Wisconsin, 53792, United States

Location

Study Officials

  • Nizar N Jarjour, MD

    University of Wisconsin, Madison

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 13, 2006

First Posted

October 17, 2006

Study Start

September 1, 2006

Primary Completion

November 1, 2006

Study Completion

November 1, 2006

Last Updated

October 5, 2015

Record last verified: 2008-10

Locations

US(1)