NCT00383955

Brief Summary

Coronary artery disease (CAD) is a silent killer that may go undetected for years. It is the leading cause of death with no limitation to geographic boundaries accounting to about 16.7 million deaths world wide. Different studies have shown that South Asians populations are more prone to CAD where it is emerging as an epidemic. According to a study conducted in Karachi it is estimated that the overall prevalence of cardiovascular diseases in Pakistan is 26.9% with 23.7% in men and 30.0% in women. However tools for measuring CAD have not being adequately validated. This study is designed to develop screening tools and to determine test characteristics of Rose Questionnaire and Minnesota Coded ECG alone and in combination for diagnosis of CAD, using MPI as gold standard in Pakistan.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
450

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2006

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

October 3, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 4, 2006

Completed
Last Updated

October 4, 2006

Status Verified

October 1, 2006

First QC Date

October 3, 2006

Last Update Submit

October 3, 2006

Conditions

Cardiovascular Disease

Eligibility Criteria

Age40 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult resident of Karachi residing in selected clusters
  • Age \> 40 years

You may not qualify if:

  • Clinical Heart Failure
  • Severe Disease e.g. Cancer
  • Pregnant or lactating women
  • People with limited mobility
  • People not willing to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Aga Khan University, Hospital

Karachi, Sindh, Pakistan

RECRUITING

MeSH Terms

Conditions

Cardiovascular Diseases

Study Officials

  • Dr. Tazeen H Jafar, MD, MPH

    Aga Khan University

    STUDY DIRECTOR

  • Dr. Shazia S Abbas

    Aga Khan University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Dr.Shazia S Abbas

CONTACT

92 21 4864860shazia.shehzad@aku.edu

Dr. Tazeen H Jafar, MD, MPH

CONTACT

92 21 4930051tazeen.jafar@aku.edu

Study Design

Study Type
observational
Time Perspective
OTHER
Sponsor Type
OTHER

Study Record Dates

First Submitted

October 3, 2006

First Posted

October 4, 2006

Study Start

October 1, 2006

Last Updated

October 4, 2006

Record last verified: 2006-10

Locations

PA(1)