NCT00379860

Brief Summary

To evaluate the safety and tolerability of multiple doses of LXR in healthy adults.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Oct 2006

Shorter than P25 for phase_1

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 21, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 25, 2006

Completed
6 days until next milestone

Study Start

First participant enrolled

October 1, 2006

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2007

Completed
Last Updated

March 9, 2007

Status Verified

March 1, 2007

First QC Date

September 21, 2006

Last Update Submit

March 8, 2007

Conditions

Healthy Subjects

Outcome Measures

Primary Outcomes (1)

  • Safety is the primary outcome.

Interventions

LXR-623DRUG

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Generally healthy adults.
  • Liver function tests, triglycerideres, and creatinine must be below upper limit of normal at screening.

You may not qualify if:

  • A history or active presence of clinically important medical disease.
  • Any metal implants or devices.
  • Claustrophobia.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

2-(2-chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole

Study Officials

  • Medical Monitor

    Wyeth is now a wholly owned subsidiary of Pfizer

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
DOUBLE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

September 21, 2006

First Posted

September 25, 2006

Study Start

October 1, 2006

Study Completion

January 1, 2007

Last Updated

March 9, 2007

Record last verified: 2007-03