Study of Effectiveness of Hand Exercises to Treat Symptoms of Hand Osteoarthritis

NCT00375947 | Completed

• 1 other identifier: ARIA-0001
• Study Type: interventional
• Target: 65
• Locations: 1 country
• Sites: 1

Brief Summary

Participants in this study will do hand exercises once per day for 16 weeks. The purpose of the study is to determine if hand exercises designed to improve range of movement and strength are an effective way to decrease functional limitations for people with hand osteoarthritis. The study will also attempt to determine if pain and stiffness are improved, and if hand strength and dexterity are improved.

Conditions

Osteoarthritis

Keywords

exercise; hand disability; arthritis; AUSCAN

Outcome Measures

Primary Outcomes (1)

• Australian-Canadian Osteoarthritis Index (AUSCAN)hand disability score at 16 weeks of exercise

Secondary Outcomes (6)

• AUSCAN hand pain score at 16 weeks of exercise

• AUSCAN hand stiffness score at 16 weeks of exercise

• Maximal and average grip strength at 16 weeks of exercise

• Maximal and average key pinch strength at 16 weeks of exercise

• Maximal and average 3-point pinch strength at 16 weeks of exercise

Study Arms (2)

1

EXPERIMENTAL

Home-based hand exercise program

Other: Hand Exercise

2

PLACEBO COMPARATOR

Sham hand cream

Other: sham hand cream

Interventions

Hand Exercise OTHER

1

sham hand cream OTHER

placebo intervention

2

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Men and women
• Ages 50 years and older
• Reside within Tampa Bay Region, Florida
• Presence of symptomatic OA as determined by the AUSCAN Index. Specifically, a hand function score of \> 225 mm for the AUSCAN VA-subscale
• Presence of radiographic hand OA, as defined by grades 2, or higher, per the Kellgren and Lawrence scale in one or more joints.

You may not qualify if:

• Concomitant rheumatic disease (e.g., rheumatoid arthritis, gout, lupus, fibromyalgia)
• Current hand or wrist injury (e.g., carpal tunnel syndrome, palmer tenosynovitis, fracture, sprain)
• Use of an assistive device such as a cane or crutch
• Has hand surgery scheduled within the 48 weeks following the start of the study
• Prior hand surgery requiring joint replacement or other instrumentation in the hands
• Received any intra-articular injection (hyaluronic acid, corticosteroid, or joint lavage) during the 3 months preceding the study
• Currently participating in another conflicting research study
• Currently using a therapeutic hand cream or practicing a hand exercise routine
• Unwilling to sign an informed consent

Sponsors & Collaborators

• The Arthritis Research Institute of America: lead

Study Sites (1)

The Arthritis Research Institute of America

Clearwater, Florida, 33755, United States

Location

Related Links

• ARIA web site

MeSH Terms

Conditions

Osteoarthritis; Motor Activity; Arthritis

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Behavior

Study Officials

• Matthew W Rogers, MS

  The Arthritis Research Institute of America

  PRINCIPAL INVESTIGATOR

• Frances V Wilder, PhD

  The Arthritis Research Institute of America

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 11, 2006
• First Posted: September 13, 2006
• Study Start: November 1, 2005
• Study Completion: April 1, 2007
• Last Updated: August 23, 2007

Record last verified: 2007-08

Locations

US (1)