NCT00367107

Brief Summary

Background: The number of adults with autism is expected to rise significantly in the near future, due to two main reasons: First, a dramatic increase in the estimates of the prevalence of autism starting in the mid 1980s; Second, the clinical diagnosis of autism was first introduced during the 1950s, and those diagnosed with autism back then are only now entering middle age. Few studies, however, have focused on the outcomes of adult autistic individuals, and very little is known about the course of autism in adulthood and on the familial burden resulting from caring for an autistic adult. We therefore propose to study adult outcomes in autism, and to examine the influence of raising an autistic individual on the parents. Working hypothesis and aims: The primary objectives of the study are:

  1. 1.Determine clinical status and functioning of autistic adults.
  2. 2.Study the influence of raising and caring for an individual with autism on the well-being of the parents.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
240

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 21, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 22, 2006

Completed
1.9 years until next milestone

Study Start

First participant enrolled

August 1, 2008

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2009

Completed
Last Updated

February 6, 2008

Status Verified

February 1, 2008

Enrollment Period

1 year

First QC Date

August 21, 2006

Last Update Submit

February 4, 2008

Conditions

Autism

Keywords

Autism spectrum disorderslong-term outcomescaregiver burdenbirth cohortnested case-control study

Eligibility Criteria

Age30 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

autisem

You may qualify if:

  • Autism or autism spectrum disorder
  • Understands the informed consent
  • Hebrew Speaker

You may not qualify if:

  • Severe acute or chronic illness
  • Substance abuse
  • In control subjects: Autism or autism spectrum disorder in subject or siblings
  • In control subjects: participating sibling

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sheba Medical Center

Tel Litwinsky, Israel

Location

MeSH Terms

Conditions

Autistic DisorderAutism Spectrum DisorderCaregiver Burden

Condition Hierarchy (Ancestors)

Child Development Disorders, PervasiveNeurodevelopmental DisordersMental DisordersStress, PsychologicalBehavioral SymptomsBehavior

Study Officials

  • Raz Gros, MD

    Mental Health Epidemiology & Psychosocial Aspects of Illness, The Gertner Institute for Epidemiology and Health Policy Research

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

August 21, 2006

First Posted

August 22, 2006

Study Start

August 1, 2008

Primary Completion

August 1, 2009

Last Updated

February 6, 2008

Record last verified: 2008-02

Locations

IL(1)