Changing Patterns of Candida Infections in Urban Medical Centers

NCT00366223 | Completed DMC

• 1 other identifier: IRB#0607092
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine the changing patterns of infection caused by Candida species in urban medical centers and its influence on patient outcomes. A retrospective cohort study design will be employed with the main outcome measure being hospital mortality. Secondary outcomes including microbiologic clearance of the infection, duration of hospitalization, and the intensive care unit (ICU) length of stay will also be assessed.

Conditions

Infection; Candida; Non Albicans Species

Keywords

infection; candida

Outcome Measures

Primary Outcomes (1)

• dead or alive

  Health status

  end of study

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

candida blood culture

You may qualify if:

• All hospitalized patients with a positive blood culture for Candida will be eligible.

You may not qualify if:

• None

Sponsors & Collaborators

• University of Pittsburgh: lead
• Pfizer: collaborator

Study Sites (1)

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

No genetic testing will be performed on any of the samples being obtained. The biologic samples will be under the control of the principal investigator of this research project. To protect confidentiality, all personal identifiers (i.e., name, social security number, and birth date) will be removed (de-identified) and replaced with a specific code number. The information linking these code numbers to the corresponding subjects' identities will be kept in a separate, secure location. The investigators on this study will keep the samples indefinitely. If a subject withdraws and provides the request in writing, samples collected and not already processed will be destroyed. All samples will be kept in the investigator's laboratory located in Scaife Hall, Room 812, 3550 Terrace Street.

MeSH Terms

Conditions

Infections; Torulopsis

Study Officials

• David L Paterson, MD

  University of Pittsburgh

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 18, 2006
• First Posted: August 21, 2006
• Study Start: August 1, 2006
• Primary Completion: June 1, 2017
• Study Completion: June 1, 2017
• Last Updated: June 12, 2018

Record last verified: 2018-06

Locations

US (1)