Hostility Reduction Program to Improve Autonomic Regulation of the Heart
Hostility Reduction and Autonomic Control of the Heart
2 other identifiers
interventional
150
0 countries
N/A
Brief Summary
Individuals who experience high hostility levels may be more prone to developing coronary artery disease (CAD) than individuals who experience low hostility levels. This study will evaluate the effectiveness of a hostility reduction treatment program on the body's ability to regulate heart activity in individuals with high levels of hostility.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Dec 1999
Longer than P75 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 1999
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2006
CompletedFirst Submitted
Initial submission to the registry
August 16, 2006
CompletedFirst Posted
Study publicly available on registry
August 17, 2006
CompletedFebruary 18, 2016
December 1, 2007
August 16, 2006
February 17, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Cardiac autonomic regulation (measured at Week 12 and at 6-month follow-up evaluation)
Interventions
Eligibility Criteria
You may qualify if:
- In good general health
- Experiences a high level of hostility according to the Spielberger Trait Anger Scale and Cook Medley Scale (greater than 1 standard deviation for each scale)
- English speaking
You may not qualify if:
- Psychiatric disorder
- Currently taking psychiatric medications
- Currently taking cardioactive medications
- Medical condition that affects the ANS
- Currently taking medications that affect the cardiovascular system
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Sloan RP, Shapiro PA, DeMeersman RE, Bagiella E, Brondolo EN, McKinley PS, Crowley O, Zhao Y, Schwartz JE, Myers MM. Impact of aerobic training on cardiovascular reactivity to and recovery from challenge. Psychosom Med. 2011 Feb-Mar;73(2):134-41. doi: 10.1097/PSY.0b013e31820a1174. Epub 2011 Jan 21.
PMID: 21257979DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Richard P. Sloan, PhD
Columbia University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Purpose
- TREATMENT
- Intervention Model
- FACTORIAL
- Sponsor Type
- NIH
Study Record Dates
First Submitted
August 16, 2006
First Posted
August 17, 2006
Study Start
December 1, 1999
Study Completion
January 1, 2006
Last Updated
February 18, 2016
Record last verified: 2007-12