NCT00364520

Brief Summary

The purpose of this study is to investigate the health effects of benzene exposure in workers in Shanghai, China.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2003

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2003

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

August 14, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 15, 2006

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
Last Updated

May 21, 2015

Status Verified

May 1, 2007

Enrollment Period

6.3 years

First QC Date

August 14, 2006

Last Update Submit

May 19, 2015

Conditions

Hematologic Diseases

Keywords

Hematologic DiseasesBenzeneGenetic Polymorphisms

Outcome Measures

Primary Outcomes (1)

  • Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers.

    Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers

    August 2003 - December 2009

Secondary Outcomes (1)

  • Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.

    August 2003 - December 2009

Study Arms (1)

Shanghai Workers

Shanghai Workers

Other: Shanghai workers

Interventions

Shanghai workersOTHER
Shanghai Workers

Eligibility Criteria

Age18 Years - 67 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Shanghai Workers

You may qualify if:

  • Worked for at least one year in a monitored environment Have at least one physical examination recorded

You may not qualify if:

  • History of cancer, radiation exposure, chemotherapy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Joint Sino-US Clinical and Molecular Laboratory (JCML)

Shanghai, 200032, China

Location

MeSH Terms

Conditions

Hematologic Diseases

Condition Hierarchy (Ancestors)

Hemic and Lymphatic Diseases

Study Officials

  • Richard D Irons, PhD

    University of Colorado at Denver and Health Sciences Ctr

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 14, 2006

First Posted

August 15, 2006

Study Start

August 1, 2003

Primary Completion

December 1, 2009

Study Completion

December 1, 2009

Last Updated

May 21, 2015

Record last verified: 2007-05

Locations

CN(1)